SCHEMBL555390

SCHEMBL555390

Nc1ccc(Oc2ccccc2Cl)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCOA1 Q15788 1/20 0.56
NCOA3 Q9Y6Q9 1/20 0.56
MAOA P21397 2/20 0.56
MAOB P27338 1/20 0.54
ALDH1A1 P00352 3/20 0.52
CYP3A4 P08684 2/20 0.52
TSHR P16473 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
PDE7A Q13946 2/20 0.50
KCNH2 Q12809 1/20 0.50
SCN5A Q14524 1/20 0.50
SCN9A Q15858 1/20 0.50
DPP4 P27487 1/20 0.50
XIAP P98170 1/20 0.49
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
MAPT P10636 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
MITF O75030 1/20 0.47
GAA P10253 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7176453 0.89 DPP4 (0.53) ALDH1A1TSHRTDP1KCNH2SCN5A
SCHEMBL29476109 0.84 MAOA (0.68) NCOA1NCOA3MAOAMAOBALDH1A1
SCHEMBL459355 0.84 MAOA (0.68) NCOA1NCOA3MAOAMAOBALDH1A1
SCHEMBL1270920 0.84 MAOA (0.68) NCOA1NCOA3MAOAMAOBALDH1A1
SCHEMBL31448129 0.84 MAOA (0.50) NCOA1NCOA3MAOAMAOBALDH1A1
SCHEMBL6826223 0.84 MAOA (0.50) NCOA1NCOA3MAOAMAOBALDH1A1
SCHEMBL9321769 0.83 HTR2A (0.53) MAOAMAOBALDH1A1DPP4XIAP
SCHEMBL6290292 0.82 MAOA (0.65) NCOA1NCOA3MAOAMAOBALDH1A1
SCHEMBL486843 0.82 MAOA (0.73) NCOA1NCOA3MAOAMAOBALDH1A1
SCHEMBL3790160 0.82 DPP4 (0.62) ALDH1A1CYP3A4TSHRTDP1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116789574-B Preparation method and application of camphorsulfonamide compound containing diphenyl ether group 南京林业大学 2024-07-30 CN claimed
CN-113880765-B 4- (1H-pyrazol-1-yl) biphenyl formamide compound containing diphenyl ether group and application thereof 南京林业大学 2023-04-28 CN claimed
EP-3797991-B1 PREPREG AND PRODUCTION METHOD THEREFOR, SLIT TAPE PREPREG, CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2025-10-29 EP disclosed
US-12448510-B2 Prepreg, method for producing same, and slit tape prepreg TORAY INDUSTRIES, INC. (JP) 2025-10-21 US disclosed
EP-3995536-B1 PREPREG AND FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2025-06-18 EP disclosed
US-20250051335-A1 TAU-TUBULIN KINASE (TTBK) INHIBITOR COMPOUNDS CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) 2025-02-13 US disclosed
CN-116789574-B Preparation method and application of camphorsulfonamide compound containing diphenyl ether group 南京林业大学 2024-07-30 CN disclosed
US-20240166798-A1 EPOXY RESIN COMPOSITION, PREPREG, AND FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2024-05-23 US disclosed
EP-4368182-A1 TAU-TUBULIN KINASE (TTBK) INHIBITOR COMPOUNDS Consejo Superior De Investigaciones Científicas - CSIC (ES) 2024-05-15 EP disclosed
EP-4314108-A1 EPOXY RESIN COMPOSITION, PREPREG, AND FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2024-02-07 EP disclosed
US-20230357561-A1 PREPREG, METHOD FOR PRODUCING SAME, AND SLIT TAPE PREPREG TORAY INDUSTRIES, INC. (JP) 2023-11-09 US disclosed
EP-1546111-A2 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES LABORATOIRES FOURNIER S.A. (FR) 2005-06-29 EP disclosed
WO-2004031160-A2 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES LABORATOIRES FOURNIER S.A. (FR) 2004-04-15 WO disclosed
US-4472433-A Phenoxyphenyl acetic acids and their medicinal use FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-09-18 US disclosed
US-4470184-A TIN ALLOYS-WEAR RESISTANCE TAIHO KOGYO, LTD. (JP) 1984-09-11 US disclosed
EP-0113920-A2 Process for the manufacture of stable solutions of cationic methine dyes, and their use in spin dyeing BAYER AG (DE) 1984-07-25 EP disclosed
EP-0008226-B1 PHENYL-ALKANOIC ACID DERIVATIVES, THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-11-02 EP disclosed
EP-0008226-A2 Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-02-20 EP disclosed
US-4169113-A STABILIZER COMPRISING ALKALINE EARTH AND GROUP 8 METAL HALIDES SOCIETA' ITALIANA RESINE S.I.R. S.P.A. (IT) 1979-09-25 US disclosed
US-3956264-A Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component BAYER AKTIENGESELLSCHAFT (DT) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250051335-A1 TAU-TUBULIN KINASE (TTBK) INHIBITOR COMPOUNDS TTBK1, TTBK2, MAPT NCOA1 1551/4885NCOA3 398/4885MAOA 1189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.