Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CXCR4 | P61073 | 8/20 | 0.42 |
| ▸ | EBP | Q15125 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ESRRA | P11474 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7252129 | 0.77 | MEN1 (0.39) | MEN1KMT2ATP53CYP3A4CYP2D6 | |
| SCHEMBL28645580 | 0.77 | ALDH1A1 (0.40) | KMT2ACYP2D6CYP2C9 | |
| SCHEMBL25378299 | 0.76 | MEN1 (0.64) | MEN1KMT2ATP53CYP3A4CYP2D6 | |
| SCHEMBL3772440 | 0.74 | — | — | |
| SCHEMBL23607588 | 0.73 | MEN1 (0.47) | MEN1KMT2ATP53CYP3A4CYP2D6 | |
| SCHEMBL5872370 | 0.72 | CXCR4 (0.47) | MEN1KMT2ATP53CYP3A4CYP2D6 | |
| SCHEMBL28647285 | 0.71 | PDCD1 (0.42) | CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6633759 | 0.70 | CXCR4 (0.46) | MEN1KMT2ATP53CYP3A4CYP2D6 | |
| SCHEMBL5013644 | 0.70 | MEN1 (0.47) | MEN1KMT2ATP53CYP3A4CYP2D6 | |
| SCHEMBL11935144 | 0.70 | CXCR4 (0.56) | MEN1KMT2ATP53CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781661-A2 | VASOPRESSIN V1A ANTAGONISTS | Ferring B.V. (NL) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006021213-A2 | VASOPRESSIN V1A ANTAGONISTS | FERRING B.V. (NL) | 2006-03-02 | — | — | WO | disclosed |