Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | LDHB | P07195 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5560071 | 0.92 | PTGS2 (0.39) | PTGS2 | |
| SCHEMBL5558659 | 0.92 | PTGS2 (0.39) | PTGS2 | |
| SCHEMBL5558629 | 0.91 | AKR1C3 (0.37) | PTGS2LDHALDHBAKR1B1 | |
| SCHEMBL5554230 | 0.88 | AKR1C3 (0.39) | LDHALDHB | |
| SCHEMBL5554255 | 0.88 | AKR1C3 (0.39) | LDHALDHB | |
| SCHEMBL5559997 | 0.87 | PPARG (0.33) | KMT2APTGS2 | |
| SCHEMBL5554440 | 0.86 | PTGS2 (0.32) | MEN1KMT2APTGS2 | |
| SCHEMBL5560536 | 0.84 | KMT2A (0.36) | MEN1KMT2APTGS2 | |
| SCHEMBL5560527 | 0.81 | PTGS2 (0.33) | PTGS2 | |
| SCHEMBL5558223 | 0.80 | PTGS2 (0.35) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1643961-A4 | COX-2 AND FAAH INHIBITORS | MICROBIA INC (US) | 2007-09-12 | — | — | EP | disclosed |
| EP-1643961-A2 | COX-2 AND FAAH INHIBITORS | Microbia, Inc. (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005002525-A2 | COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2005-01-13 | — | — | WO | disclosed |