Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | FPR1 | P21462 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5558485 | 0.91 | PPARG (0.36) | POLBAKR1C3AKR1C2PPARGPTGS2 | |
| SCHEMBL5558706 | 0.91 | PPARG (0.36) | POLBAKR1C3AKR1C2PPARGPTGS2 | |
| SCHEMBL5554459 | 0.90 | PPARG (0.38) | POLBAKR1C3AKR1C2PPARGMEN1 | |
| SCHEMBL5554806 | 0.83 | CNR2 (0.36) | POLBAKR1C3AKR1C2MEN1LMNA | |
| SCHEMBL5559997 | 0.83 | PPARG (0.33) | AKR1C3AKR1C2PPARGLMNAKMT2A | |
| SCHEMBL5558223 | 0.79 | PTGS2 (0.35) | AKR1C3AKR1C2PTGS2 | |
| SCHEMBL5560625 | 0.78 | MAPT (0.37) | POLBAKR1C3AKR1C2PPARGMEN1 | |
| SCHEMBL5554632 | 0.78 | PTGS1 (0.39) | AKR1C3AKR1C2PPARGMEN1LMNA | |
| SCHEMBL5558850 | 0.77 | AKR1C3 (0.40) | AKR1C3AKR1C2LMNAPTGS2 | |
| SCHEMBL5554036 | 0.76 | PTGS2 (0.42) | AKR1C3AKR1C2PPARGPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1643961-A4 | COX-2 AND FAAH INHIBITORS | MICROBIA INC (US) | 2007-09-12 | — | — | EP | disclosed |
| EP-1643961-A2 | COX-2 AND FAAH INHIBITORS | Microbia, Inc. (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005002525-A2 | COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2005-01-13 | — | — | WO | disclosed |