Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 9/20 | 0.36 |
| ▸ | QPCTL | Q9NXS2 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzimidazole SCHEMBL29218507 | 0.78 | MMP12 (0.47) | MMP12QPCTQPCTLKDM4EALDH1A1 | |
| Benzimidazole SCHEMBL6009 | 0.78 | — | — | |
| Benzimidazole SCHEMBL461969 | 0.78 | SMN1; SMN2 (0.50) | MMP12IDO1TDO2QPCTQPCTL | |
| Benzimidazole SCHEMBL29408372 | 0.78 | — | — | |
| Benzimidazole SCHEMBL10931770 | 0.78 | SMN1; SMN2 (0.50) | MMP12IDO1TDO2QPCTQPCTL | |
| Benzimidazole SCHEMBL29358377 | 0.78 | — | — | |
| Benzimidazole SCHEMBL28381628 | 0.77 | MMP12 (0.46) | MMP12IDO1TDO2QPCTQPCTL | |
| Benzimidazole SCHEMBL5040740 | 0.77 | KDM4E (0.47) | MMP12QPCTQPCTLKDM4EALDH1A1 | |
| Benzimidazole SCHEMBL376958 | 0.77 | MMP12 (0.46) | MMP12QPCTQPCTLKDM4EALDH1A1 | |
| Benzimidazole SCHEMBL23673327 | 0.76 | SMN1; SMN2 (0.48) | MMP12IDO1TDO2QPCTQPCTL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524899-B2 | Oligopeptide containing fused 6-membered ring forming complexes with double stranded dna; complexes can be used for identification of specific dsDNA sequences, inhibiting gene transcription, therapeutic for inhibiting proliferation of undesired cells or modulation of expression of specific gene | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2013-09-03 | — | — | US | disclosed |
| EP-1599474-B1 | Heterocyclic oligomeric compounds for DNA recognition | CALIFORNIA INST OF TECHN (US) | 2013-04-24 | — | — | EP | disclosed |
| EP-1599474-A4 | ALTERNATIVE HETEROCYCLES FOR DNA RECOGNITION | CALIFORNIA INST OF TECHN (US) | 2007-08-22 | — | — | EP | disclosed |
| EP-1599474-A2 | ALTERNATIVE HETEROCYCLES FOR DNA RECOGNITION | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2005-11-30 | — | — | EP | disclosed |
| US-20050026174-A1 | Alternative heterocycles for DNA recognition | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2005-02-03 | — | — | US | disclosed |
| WO-2004078943-A2 | ALTERNATIVE HETEROCYCLES FOR DNA RECOGNITION | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2004-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026174-A1 | Alternative heterocycles for DNA recognition | DDB1, PCNA, DNA2 | MMP12 3109/4885IDO1 4424/4885TDO2 4061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.