Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | PDE1A | P54750 | 1/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
| ▸ | FOS | P01100 | 1/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 4/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5554648 | 0.88 | CYP2C9 (0.46) | BCL2L1KDM4EALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL5554103 | 0.84 | BCL2L1 (0.67) | BCL2L1KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL5559504 | 0.83 | BCL2L1 (0.74) | BCL2L1KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL5559075 | 0.82 | BCL2L1 (0.58) | BCL2L1KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL5554198 | 0.80 | BCL2L1 (0.56) | BCL2L1KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL5560834 | 0.77 | BCL2L1 (0.51) | BCL2L1KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL19420098 | 0.76 | BCL2L1 (0.75) | BCL2L1KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL19425571 | 0.74 | BCL2L1 (0.83) | BCL2L1KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL8736604 | 0.74 | TDP1 (0.53) | BCL2L1KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL254749 | 0.74 | BCL2L1 (1.00) | BCL2L1KDM4EALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594512-A4 | COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTION | KEMIA INC (US) | 2007-07-11 | — | — | EP | disclosed |
| EP-1594512-A2 | COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTION | Kemia, INC. (US) | 2005-11-16 | — | — | EP | disclosed |
| US-20040248850-A1 | Compounds for the treatment of HIV infection | KEMIA, INC. | 2004-12-09 | — | — | US | disclosed |
| WO-2004071426-A2 | COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTION | KEMIA INC. (US) | 2004-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248850-A1 | Compounds for the treatment of HIV infection | CCR5, CD4, HAVCR2 | BCL2L1 2807/4885KDM4E 2338/4885ALDH1A1 1251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.