Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 4/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | PDE1A | P54750 | 1/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6798515 | 0.81 | NPC1 (0.54) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL8733973 | 0.77 | TDP1 (0.51) | TDP1KDM4EALDH1A1HPGDBCL2L1 | |
| SCHEMBL5650340 | 0.76 | ALDH1A1 (0.57) | KDM4EALDH1A1PTGDR2L3MBTL1 | |
| SCHEMBL5554103 | 0.76 | BCL2L1 (0.67) | TDP1KDM4EALDH1A1HPGDBCL2L1 | |
| SCHEMBL5559504 | 0.75 | BCL2L1 (0.74) | TDP1KDM4EALDH1A1HPGDBCL2L1 | |
| SCHEMBL7906854 | 0.75 | NPC1 (0.60) | KDM4EALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL5559075 | 0.74 | BCL2L1 (0.58) | TDP1KDM4EALDH1A1HPGDBCL2L1 | |
| SCHEMBL5554775 | 0.74 | BCL2L1 (0.58) | TDP1KDM4EALDH1A1HPGDBCL2L1 | |
| SCHEMBL14787928 | 0.73 | ALDH1A1 (0.63) | TDP1KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL5554198 | 0.73 | BCL2L1 (0.56) | TDP1KDM4EALDH1A1HPGDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1200106-A | Phenoxy acetic acids as aldose reductase inhibitors and antihyperglycemic agents | AMERICAN HOME PROD (US) | 1998-11-25 | — | — | CN | disclosed |
| EP-0847379-A1 | PHENOXY ACETIC ACIDS AS ALDOSE REDUCTASE INHIBITORS AND ANTIHYPERGLYCEMIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-06-17 | — | — | EP | disclosed |
| EP-0847379-A1 | PHENOXY ACETIC ACIDS AS ALDOSE REDUCTASE INHIBITORS AND ANTIHYPERGLYCEMIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-06-17 | — | — | EP | disclosed |
| US-5677342-A | ANTIDIABETIC AGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-10-14 | — | — | US | disclosed |
| US-5677342-A | ANTIDIABETIC AGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-10-14 | — | — | US | disclosed |
| WO-1997008126-A1 | PHENOXY ACETIC ACIDS AS ALDOSE REDUCTASE INHIBITORS AND ANTIHYPERGLYCEMIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-03-06 | — | — | WO | disclosed |
| WO-1997008126-A1 | PHENOXY ACETIC ACIDS AS ALDOSE REDUCTASE INHIBITORS AND ANTIHYPERGLYCEMIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-03-06 | — | — | WO | disclosed |