SCHEMBL5554872

SCHEMBL5554872

CCN(CC)c1ccc(C)c(C(c2ccc(O)cc2)c2cc(N(CC)CC)ccc2C)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
CYP3A4 P08684 2/20 0.44
S100B P04271 1/20 0.42
TSHR P16473 1/20 0.42
GRK6 P43250 1/20 0.40
MAPT P10636 4/20 0.40
RAB9A P51151 2/20 0.40
ESRRG P62508 1/20 0.39
CNR2 P34972 5/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
BACE1 P56817 1/20 0.38
LMNA P02545 2/20 0.37
ESR1 P03372 1/20 0.37
CYP1A2 P05177 1/20 0.37
PGR P06401 1/20 0.37
CHRM2 P08172 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
AR P10275 1/20 0.37
CYP2D6 P10635 1/20 0.37
CHRM1 P11229 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5007900 0.91 GRK6 (0.48) ALDH1A1CYP3A4S100BTSHRGRK6
SCHEMBL5554863 0.88 S100B (0.46) ALDH1A1CYP3A4S100BTSHRGRK6
SCHEMBL11520124 0.87 GRK6 (0.48) ALDH1A1CYP3A4S100BTSHRGRK6
SCHEMBL5555831 0.86 S100B (0.44) ALDH1A1CYP3A4S100BTSHRGRK6
SCHEMBL5556669 0.85 S100B (0.46) ALDH1A1CYP3A4S100BTSHRGRK6
SCHEMBL5097347 0.85 LMNA (0.49) ALDH1A1S100BTSHRGRK6MAPT
SCHEMBL237533 0.84 S100B (0.45) ALDH1A1CYP3A4S100BTSHRGRK6
SCHEMBL5667453 0.84 CNR2 (0.42) ALDH1A1CYP3A4S100BTSHRGRK6
SCHEMBL81552 0.84 S100B (0.53) ALDH1A1CYP3A4S100BTSHRGRK6
SCHEMBL11275262 0.83 CNR2 (0.45) ALDH1A1S100BTSHRGRK6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1803034-A2 HOLOGRAPHIC STORAGE MEDIUM General Electric Company (US) 2007-07-04 EP disclosed
WO-2006044243-A2 HOLOGRAPHIC STORAGE MEDIUM GENERAL ELECTRIC COMPANY A CORPORATION OF THE STATE OF NEW YORK (US) 2006-04-27 WO disclosed
US-20060078802-A1 Holographic storage medium SABIC INNOVATIVE PLASTICS IP B.V. 2006-04-13 US disclosed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed