Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 9/20 | 0.83 |
| ▸ | SLC6A9 | P48067 | 8/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | IDE | P14735 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924591 | 0.93 | SLC6A5 (0.85) | SLC6A5SLC6A9ALDH1A1KDM4EIDE | |
| SCHEMBL3916574 | 0.91 | SLC6A5 (1.00) | SLC6A5SLC6A9IDEPAX8SMN1; SMN2 | |
| SCHEMBL3925242 | 0.89 | SLC6A5 (0.76) | SLC6A5SLC6A9ALDH1A1KDM4EIDE | |
| SCHEMBL27859058 | 0.88 | SLC6A5 (0.78) | SLC6A5SLC6A9ALDH1A1KDM4EIDE | |
| SCHEMBL3927761 | 0.87 | IDE (0.69) | SLC6A5SLC6A9ALDH1A1IDEPAX8 | |
| SCHEMBL4422290 | 0.84 | LMNA (0.81) | SLC6A5SLC6A9ALDH1A1IDEMAPT | |
| SCHEMBL27643069 | 0.84 | IDE (0.65) | SLC6A5SLC6A9ALDH1A1IDEMAPT | |
| SCHEMBL27643071 | 0.82 | IDE (0.63) | SLC6A5SLC6A9ALDH1A1IDEMAPT | |
| SCHEMBL13687883 | 0.82 | SLC6A5 (1.00) | SLC6A5SLC6A9IDEPAX8SMN1; SMN2 | |
| SCHEMBL5044849 | 0.81 | SLC6A5 (0.81) | SLC6A5SLC6A9IDEPAX8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663232-B1 | 1-(2-AMINO-BENZOYL)-PIPERAZINE DERIVATIVES AS GLYCINE UPTAKE INHIBITORS FOR THE TREATMENT OF PSYCHOSES | HOFFMANN LA ROCHE (CH) | 2007-10-03 | — | — | EP | claimed |
| EP-1663232-B1 | 1-(2-AMINO-BENZOYL)-PIPERAZINE DERIVATIVES AS GLYCINE UPTAKE INHIBITORS FOR THE TREATMENT OF PSYCHOSES | HOFFMANN LA ROCHE (CH) | 2007-10-03 | — | — | EP | disclosed |