Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | FURIN | P09958 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3395919 | 0.96 | L3MBTL1 (0.43) | TDP1L3MBTL1ATMFURINMET | |
| Butanedione SCHEMBL28856348 | 0.88 | FURIN (0.38) | TDP1L3MBTL1ATMFURINMET | |
| SCHEMBL3393415 | 0.87 | TP53 (0.36) | CES2CES1CA12CA1CA2 | |
| SCHEMBL11139683 | 0.85 | CES1 (0.46) | TDP1L3MBTL1ATMKMT2AMEN1 | |
| SCHEMBL84542 | 0.85 | CES1 (0.46) | TDP1L3MBTL1ATMKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL10824719 | 0.83 | CES1 (0.44) | TDP1L3MBTL1ATMKMT2AMEN1 | |
| SCHEMBL9117144 | 0.82 | CES2 (0.57) | L3MBTL1KMT2AMEN1CES2CES1 | |
| SCHEMBL4092403 | 0.82 | PARP1 (0.53) | TDP1KMT2AMEN1HDAC8HDAC6 | |
| SCHEMBL28864381 | 0.82 | PARP1 (0.53) | L3MBTL1KMT2AMEN1POLBKDM4E | |
| SCHEMBL10792089 | 0.82 | PARP1 (0.53) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778755-A1 | POLYACYLURETHANES BASED ON DIISOCYANATES AND POLYESTERPOLYOLS | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006009443-A1 | POLYACYLURETHANES BASED ON DIISOCYANATES AND POLYESTERPOLYOLS | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2006-01-26 | — | — | WO | disclosed |