Eupatorin

Eupatorin

SCHEMBL555597

COc1ccc(-c2cc(=O)c3c(O)c(OC)c(OC)cc3o2)cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 4/20 1.00
CYP1B1 Q16678 4/20 1.00
FLT3 P36888 2/20 1.00
AURKA O14965 1/20 1.00
KDR P35968 1/20 1.00
AURKB Q96GD4 1/20 1.00
CYP1A2 P05177 2/20 0.84
OPRD1 P41143 1/20 0.84
KDM4E B2RXH2 3/20 0.78
POLB P06746 3/20 0.78
MAPT P10636 3/20 0.78
ADORA3 P0DMS8 1/20 0.78
HDAC6 Q9UBN7 2/20 0.74
RECQL P46063 2/20 0.73
HSD17B2 P37059 1/20 0.71
TAS2R31 P59538 1/20 0.71
MEN1 O00255 2/20 0.70
KMT2A Q03164 2/20 0.70
KDM1A O60341 1/20 0.70
ABCC1 P33527 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Eupatorin SCHEMBL30334912 1.00 CYP1A1 (1.00) CYP1A1CYP1B1FLT3AURKAKDR
Eupatorin SCHEMBL29386042 1.00 CYP1A1 (1.00) CYP1A1CYP1B1FLT3AURKAKDR
SCHEMBL8069022 0.93 FLT3 (0.86) CYP1A1CYP1B1FLT3AURKAKDR
SCHEMBL30799172 0.93 FLT3 (0.86) CYP1A1CYP1B1FLT3AURKAKDR
Cirsiliol SCHEMBL29928874 0.93 CYP1A1 (0.86) CYP1A1CYP1B1FLT3AURKAKDR
Cirsiliol SCHEMBL1614677 0.93 CYP1A1 (0.86) CYP1A1CYP1B1FLT3AURKAKDR
SCHEMBL30082755 0.93 CYP1A1 (1.00) CYP1A1CYP1B1FLT3AURKAKDR
SCHEMBL1764630 0.93 CYP1A1 (1.00) CYP1A1CYP1B1FLT3AURKAKDR
SCHEMBL3131502 0.91 CYP1B1 (1.00) CYP1A1CYP1B1FLT3AURKAKDR
SCHEMBL34468184 0.91 CYP1B1 (1.00) CYP1A1CYP1B1FLT3AURKAKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 506 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4698662-A2 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES AskBio Inc. (US) 2026-02-25 EP claimed
CN-116103161-B Plant endophytic fungus for producing eupatorium and application thereof 三峡大学 2025-06-03 CN claimed
CN-120058823-A Synthesis method of thioglycosyl eupatorin derivatives and application of thioglycosyl eupatorin derivatives in hypoglycemic drugs 三峡大学 2025-05-30 CN claimed
WO-2024220449-A9 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES AskBio Inc. (US) 2025-04-03 WO claimed
US-20250051551-A1 IMPROVED POLYMER COMPOSITES WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2025-02-13 US claimed
US-20250009892-A1 DELIVERY SYSTEMS AND METHODS FOR REACTIVE HYDROXYL-CONTAINING COMPOUNDS UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2025-01-09 US claimed
CN-117368344-B Method for constructing finger print of mugwort leaf medicinal material and decoction pieces, standard decoction and formula particles thereof 广东一方制药有限公司 2025-01-07 CN claimed
CN-119104639-A Method for measuring content of phenylpropanoids and flavonoid components in mugwort leaf 广东一方制药有限公司 2024-12-10 CN claimed
WO-2024220449-A2 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES ASKLEPIOS BIOPHARMACEUTICAL, INC. (US) 2024-10-24 WO claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
EP-2250505-A1 CANCER DETECTION METHODS AND TECHNIQUES Care Technologies Inc (CA) 2010-11-17 EP claimed
WO-2010056858-A2 BIOLUMINESCENCE IMAGING-BASED SCREENING ASSAY AND INHIBITORS OF ABCG2 THE JOHNS HOPKINS UNIVERSITY (US) 2010-05-20 WO claimed
WO-2009103984-A1 CANCER DETECTION METHODS AND TECHNIQUES CARE TECHNOLOGIES INC (CA) 2009-08-27 WO claimed
US-6872771-B1 Tire with rubber containing flavone THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-03-29 US claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
JP-2003504327-A 2003-02-04 JP claimed
EP-1223928-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS Prendergast, Patrick Thomas (IE) 2002-07-24 EP claimed
US-20020028775-A1 Compositions and methods for the control of smoking KING MICHAEL GLENN (AU) 2002-03-07 US claimed
WO-2001003681-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS PRENDERGAST PATRICK T (IE) 2001-01-18 WO claimed
US-4617293-A Flavonoid phosphate salts of aminoglycoside antibiotics MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1986-10-14 US claimed