Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 5/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | RBP4 | P02753 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1176642 | 0.96 | TRPA1 (0.39) | TRPA1SCN5ASCN9AGSK3BRBP4 | |
| SCHEMBL5046515 | 0.96 | TRPA1 (0.39) | TRPA1SCN5ASCN9AGSK3BRBP4 | |
| Formic Acid SCHEMBL5557691 | 0.93 | RBP4 (0.41) | GSK3BRBP4CFTRLRRK2 | |
| Formic Acid SCHEMBL5562792 | 0.90 | DYRK1A (0.39) | GSK3BRBP4JAK2JAK1TYK2 | |
| SCHEMBL1177055 | 0.89 | RBP4 (0.43) | GSK3BRBP4CFTRLRRK2 | |
| SCHEMBL12628022 | 0.89 | RBP4 (0.43) | GSK3BRBP4CFTRLRRK2 | |
| SCHEMBL1176036 | 0.89 | RBP4 (0.43) | GSK3BRBP4CFTRLRRK2 | |
| Formic Acid SCHEMBL5562459 | 0.89 | GSK3B (0.41) | GSK3BRBP4 | |
| Formic Acid SCHEMBL5556994 | 0.86 | GSK3B (0.39) | TRPA1GSK3BRBP4 | |
| SCHEMBL1176208 | 0.86 | DYRK1A (0.41) | GSK3BRBP4JAK2JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697378-B1 | INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, AND 1,2-BENZISOTHIAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARM CORP (US) | 2007-11-21 | — | — | EP | claimed |