Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 17/20 | 0.39 |
| ▸ | WNT1 | P04628 | 6/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1176422 | 0.97 | GSK3B (0.53) | GSK3BDYRK1AWNT1KCNH2 | |
| SCHEMBL5043498 | 0.97 | GSK3B (0.53) | GSK3BDYRK1AWNT1KCNH2 | |
| Formic Acid SCHEMBL5562317 | 0.93 | GSK3B (0.43) | GSK3BDYRK1AWNT1 | |
| SCHEMBL1176284 | 0.90 | GSK3B (0.45) | GSK3BDYRK1AWNT1 | |
| SCHEMBL5043690 | 0.90 | GSK3B (0.45) | GSK3BDYRK1AWNT1 | |
| Formic Acid SCHEMBL5563457 | 0.83 | DYRK1A (0.52) | GSK3BDYRK1AWNT1 | |
| Formic Acid SCHEMBL5557042 | 0.82 | DYRK1A (0.53) | GSK3BDYRK1AWNT1 | |
| Formic Acid SCHEMBL5561679 | 0.82 | DYRK1A (0.40) | GSK3BDYRK1AWNT1 | |
| Formic Acid SCHEMBL5561803 | 0.81 | CDK2 (0.40) | GSK3BDYRK1AWNT1 | |
| Formic Acid SCHEMBL5561851 | 0.81 | PRKAG1 (0.54) | GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697378-B1 | INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, AND 1,2-BENZISOTHIAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARM CORP (US) | 2007-11-21 | — | — | EP | claimed |