Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 13/20 | 0.39 |
| ▸ | WNT1 | P04628 | 7/20 | 0.39 |
| ▸ | GSK3B | P49841 | 4/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047046 | 0.96 | CDK2 (0.42) | CDK2GSK3ADYRK1AWNT1GSK3B | |
| SCHEMBL1176497 | 0.96 | CDK2 (0.42) | CDK2GSK3ADYRK1AWNT1GSK3B | |
| Formic Acid SCHEMBL5556316 | 0.93 | CDK2 (0.46) | CDK2GSK3AGSK3BCHEK1CNR2 | |
| SCHEMBL5044511 | 0.89 | CDK2 (0.48) | CDK2GSK3AGSK3BCHEK1GABRA1 | |
| SCHEMBL1176625 | 0.89 | CDK2 (0.48) | CDK2GSK3AGSK3BCHEK1GABRA1 | |
| Formic Acid SCHEMBL5563457 | 0.86 | DYRK1A (0.52) | DYRK1AWNT1GSK3B | |
| Formic Acid SCHEMBL5561679 | 0.85 | DYRK1A (0.40) | GSK3ADYRK1AWNT1GSK3B | |
| Formic Acid SCHEMBL5557042 | 0.84 | DYRK1A (0.53) | DYRK1AWNT1GSK3B | |
| Formic Acid SCHEMBL5563474 | 0.83 | DYRK1A (0.55) | DYRK1AWNT1GSK3B | |
| Formic Acid SCHEMBL5563261 | 0.82 | GSK3B (0.40) | CDK2GSK3ADYRK1AWNT1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697378-B1 | INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, AND 1,2-BENZISOTHIAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARM CORP (US) | 2007-11-21 | — | — | EP | claimed |