Ether

Ether

SCHEMBL5557006

CCOCC.COC(C)C

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
ALDH1A1 P00352 1/20 0.33
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL10711098 0.83 LMNA (0.42) LMNAALDH1A1THRB
Ether SCHEMBL5016712 0.83 LMNA (0.42) LMNAALDH1A1THRB
SCHEMBL6060043 0.82 HSD17B10 (0.44) LMNAALDH1A1
Ether SCHEMBL7738174 0.81 LMNA (0.44) LMNAALDH1A1THRB
Ether SCHEMBL8662793 0.79 LMNA (0.37) LMNAALDH1A1THRB
Ether SCHEMBL437946 0.79 LMNA (0.37) LMNAALDH1A1THRB
Ether SCHEMBL9793363 0.79 LMNA (0.37) LMNAALDH1A1THRB
Ether SCHEMBL4405938 0.79 THRB (0.39) LMNAALDH1A1THRB
Ether SCHEMBL20136143 0.77 ALDH1A1 (0.42) LMNAALDH1A1THRB
Ether SCHEMBL9750502 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7189339-B2 Compositions comprising 1,1,1,3,3-pentafluorobutane and use of these compositions SOLVAY SA (BE) 2007-03-13 US claimed
CN-101124303-A Conversion of petroleum resid to usable oils with ultrasound SULPHCO INC (US) 2008-02-13 CN disclosed
EP-0684237-B1 MORPHOLINE DERIVATIVE YAMANOUCHI PHARMA CO LTD (JP) 1999-12-08 EP disclosed
US-5521180-A Morpholine derivative YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1996-05-28 US disclosed
EP-0684237-A1 MORPHOLINE DERIVATIVE YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1995-11-29 EP disclosed