Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 6/20 | 0.47 |
| ▸ | DNMT3L | Q9UJW3 | 4/20 | 0.47 |
| ▸ | DNMT3A | Q9Y6K1 | 4/20 | 0.47 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3239601 | 0.84 | MMP9 (0.54) | MEN1KMT2AMMP1MMP9 | |
| SCHEMBL5558936 | 0.83 | DNMT1 (0.47) | DNMT1DNMT3LDNMT3AEHMT1MAPT | |
| SCHEMBL5558076 | 0.82 | HDAC1 (0.52) | MEN1ALDH1A1KMT2ARAB9AALOX12 | |
| SCHEMBL3245888 | 0.81 | MMP9 (0.49) | DNMT1DNMT3LDNMT3AEHMT1MEN1 | |
| SCHEMBL5559910 | 0.80 | DNMT1 (0.45) | DNMT1DNMT3LDNMT3AEHMT1MAPT | |
| SCHEMBL13312577 | 0.77 | MEN1 (0.46) | RAD52MEN1ALDH1A1KMT2AMAPT | |
| Iodide SCHEMBL3501443 | 0.76 | ROCK1 (0.46) | RAD52MEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL3239682 | 0.76 | DNMT1 (0.53) | DNMT1DNMT3LDNMT3AMEN1KMT2A | |
| SCHEMBL5558113 | 0.71 | CD38 (0.44) | MAPT | |
| SCHEMBL3499609 | 0.67 | DNMT1 (0.36) | DNMT1DNMT3LDNMT3ARAD52MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509516-B1 | INHIBITORS OF THE GPIB -VWF INTERACTION, THEIR PREPARATION AND USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-01-31 | — | — | EP | claimed |