Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 4/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 14/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | FPR1 | P21462 | 1/20 | 0.41 |
| ▸ | FPR3 | P25089 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5559910 | 0.88 | DNMT1 (0.45) | OPRL1OPRM1OPRK1MAPTOPRD1 | |
| SCHEMBL5558101 | 0.86 | CD38 (0.48) | CD38OPRL1OPRM1OPRK1PIK3CA | |
| SCHEMBL5558076 | 0.84 | HDAC1 (0.52) | CD38HDAC6 | |
| SCHEMBL5558936 | 0.84 | DNMT1 (0.47) | OPRL1OPRM1OPRK1MAPTOPRD1 | |
| SCHEMBL3243944 | 0.81 | MMP9 (0.46) | OPRL1OPRM1OPRK1MAPTOPRD1 | |
| SCHEMBL3233220 | 0.80 | MMP9 (0.51) | OPRL1OPRM1OPRK1MAPTOPRD1 | |
| SCHEMBL5558052 | 0.71 | DNMT1 (0.47) | MAPT | |
| SCHEMBL3239682 | 0.69 | DNMT1 (0.53) | — | |
| SCHEMBL3239601 | 0.68 | MMP9 (0.54) | OPRL1 | |
| SCHEMBL3241944 | 0.67 | DNMT1 (0.55) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509516-B1 | INHIBITORS OF THE GPIB -VWF INTERACTION, THEIR PREPARATION AND USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-01-31 | — | — | EP | claimed |