Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 5/20 | 0.48 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.47 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.47 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 10/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5558113 | 0.86 | CD38 (0.44) | CD38OPRL1PIK3CAMTOROPRM1 | |
| SCHEMBL3241944 | 0.80 | DNMT1 (0.55) | DNMT1DNMT3LDNMT3AOPRL1MEN1 | |
| SCHEMBL5559910 | 0.73 | DNMT1 (0.45) | DNMT1DNMT3LDNMT3AOPRL1PIK3CA | |
| SCHEMBL5558076 | 0.70 | HDAC1 (0.52) | CD38MEN1KMT2A | |
| SCHEMBL6128195 | 0.70 | MEN1 (0.72) | MEN1KMT2A | |
| SCHEMBL20680339 | 0.69 | CD38 (0.59) | CD38 | |
| SCHEMBL5558936 | 0.69 | DNMT1 (0.47) | DNMT1DNMT3LDNMT3AOPRL1PIK3CA | |
| SCHEMBL14818974 | 0.68 | MEN1 (0.60) | MEN1KMT2AOPRK1 | |
| SCHEMBL3243944 | 0.67 | MMP9 (0.46) | OPRL1MEN1KMT2AOPRM1OPRK1 | |
| SCHEMBL20680283 | 0.66 | CD38 (0.84) | CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509516-B1 | INHIBITORS OF THE GPIB -VWF INTERACTION, THEIR PREPARATION AND USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-01-31 | — | — | EP | claimed |