Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5555276 | 0.78 | DAO (0.46) | DAOHCAR3HCAR2 | |
| SCHEMBL5556071 | 0.78 | ALAD (0.33) | DAO | |
| SCHEMBL15319336 | 0.76 | KMO (0.51) | SLC6A3 | |
| SCHEMBL15319135 | 0.76 | KMO (0.51) | SLC6A3 | |
| SCHEMBL5556099 | 0.75 | NPC1 (0.30) | — | |
| SCHEMBL5561860 | 0.73 | GSK3B (0.40) | — | |
| SCHEMBL5556615 | 0.73 | DAO (0.47) | DAO | |
| SCHEMBL5555505 | 0.72 | DAO (0.49) | DAOSLC6A3 | |
| SCHEMBL5556073 | 0.72 | MAPT (0.40) | — | |
| SCHEMBL6031208 | 0.70 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565451-B1 | HALOTHIENOYL-CYCLOPROPANE-1-CARBOXYLIC ACID DERIVATIVES | NEWRON PHARM SPA (IT) | 2007-05-09 | — | — | EP | claimed |
| US-20060116329-A1 | Halothenoyl-cyclopropane-1-carboxylic acid derivatives | NEWRON PHARMACEUTICALS, S.P.A. (IT) | 2006-06-01 | — | — | US | claimed |
| EP-1565451-A1 | HALOTHENOYL-CYCLOPROPANE-1-CARBOXYLIC ACID DERIVATIVES | Newron Pharmaceuticals S.p.A. (IT) | 2005-08-24 | — | — | EP | claimed |
| WO-2004048361-A1 | HALOTHENOYL-CYCLOPROPANE-1-CARBOXYLIC ACID DERIVATIVES | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2004-06-10 | — | — | WO | claimed |
| EP-1424333-A1 | Halothenoyl-cyclopropane-1-carboxylic acid derivatives | Newron Pharmaceuticals S.p.A. (IT) | 2004-06-02 | — | — | EP | claimed |
| EP-1565451-B1 | HALOTHIENOYL-CYCLOPROPANE-1-CARBOXYLIC ACID DERIVATIVES | NEWRON PHARM SPA (IT) | 2007-05-09 | — | — | EP | disclosed |
| US-20060116329-A1 | Halothenoyl-cyclopropane-1-carboxylic acid derivatives | NEWRON PHARMACEUTICALS, S.P.A. (IT) | 2006-06-01 | — | — | US | disclosed |
| EP-1565451-A1 | HALOTHENOYL-CYCLOPROPANE-1-CARBOXYLIC ACID DERIVATIVES | Newron Pharmaceuticals S.p.A. (IT) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004048361-A1 | HALOTHENOYL-CYCLOPROPANE-1-CARBOXYLIC ACID DERIVATIVES | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2004-06-10 | — | — | WO | disclosed |
| EP-1424333-A1 | Halothenoyl-cyclopropane-1-carboxylic acid derivatives | Newron Pharmaceuticals S.p.A. (IT) | 2004-06-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116329-A1 | Halothenoyl-cyclopropane-1-carboxylic acid derivatives | KMO, HAO1, DAO | DAO 3/4885HCAR3 44/4885HCAR2 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.