Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14812115 | 1.00 | L3MBTL1 (0.61) | L3MBTL1POLBHTTALDH1A1KLK5 | |
| SCHEMBL14811830 | 1.00 | L3MBTL1 (0.61) | L3MBTL1POLBHTTALDH1A1KLK5 | |
| SCHEMBL1278442 | 0.94 | L3MBTL1 (0.55) | L3MBTL1POLBHTTALDH1A1KLK5 | |
| SCHEMBL1290904 | 0.94 | L3MBTL1 (0.55) | L3MBTL1POLBHTTALDH1A1KLK5 | |
| SCHEMBL24108598 | 0.86 | — | — | |
| SCHEMBL149411 | 0.86 | — | — | |
| SCHEMBL28051654 | 0.86 | — | — | |
| SCHEMBL940890 | 0.82 | L3MBTL1 (0.45) | L3MBTL1POLBHTTALDH1A1MEN1 | |
| SCHEMBL30693669 | 0.81 | L3MBTL1 (0.59) | L3MBTL1POLBHTTALDH1A1KLK5 | |
| SCHEMBL27774970 | 0.81 | L3MBTL1 (0.59) | L3MBTL1POLBHTTALDH1A1KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023158722-A2 | PROCESSES FOR PREPARATION OF AVACOPAN AND INTERMEDIATES THEREOF | TEVA PHARMACEUTICALS INTERNATIONAL GMBH (CH) | 2023-08-24 | — | — | WO | claimed |
| CN-103732577-B | As effective hdac inhibitor carrying lactams thio derivative and they as medicine purposes | 希格马托制药工业公司 | 2017-04-05 | — | — | CN | claimed |
| EP-2758371-B1 | NEW THIO DERIVATIVES BEARING LACTAMS AS POTENT HDAC INHIBITORS AND THEIR USES AS MEDICAMENTS | SIGMA TAU IND FARMACEUTI (IT) | 2016-06-15 | — | — | EP | claimed |
| US-8927533-B2 | Thio derivatives bearing lactams as potent HDAC inhibitors and their uses as medicaments | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2015-01-06 | — | — | US | claimed |
| EP-2758371-A1 | NEW THIO DERIVATIVES BEARING LACTAMS AS POTENT HDAC INHIBITORS AND THEIR USES AS MEDICAMENTS | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. (IT) | 2014-07-30 | — | — | EP | claimed |
| WO-2013041480-A1 | NEW THIO DERIVATIVES BEARING LACTAMS AS POTENT HDAC INHIBITORS AND THEIR USES AS MEDICAMENTS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2013-03-28 | — | — | WO | claimed |
| EP-2029235-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AMIDE | L'Oréal (FR) | 2009-03-04 | — | — | EP | claimed |
| WO-2007135296-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AMIDE | L'OREAL (FR) | 2007-11-29 | — | — | WO | claimed |
| EP-4294804-B1 | PYRIDONE COMPOUNDS AND METHODS OF USE | EXELIXIS INC (US) | 2026-04-08 | — | — | EP | disclosed |
| EP-4680375-A1 | SYSTEM AND METHOD FOR FLUID CAPTURE | GE Vernova Technology GmbH (CH) | 2026-01-21 | — | — | EP | disclosed |
| EP-4680252-A1 | SYSTEM AND METHOD FOR FLUID CAPTURE | GE Vernova Infrastructure Technology LLC (US) | 2026-01-21 | — | — | EP | disclosed |
| US-20250346602-A1 | LACTAM SUBSTITUTED IMIDAZOPYRIDAZINE IL-17A MODULATORS AND USES THEREOF | DICE ALPHA INC (US) | 2025-11-13 | — | — | US | disclosed |
| EP-4629980-A1 | ANTIMICROBIAL COMPOUNDS | SRI International (US) | 2025-10-15 | — | — | EP | disclosed |
| US-12421232-B2 | Kinase inhibitor compounds and compositions and methods of use | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2025-09-23 | — | — | US | disclosed |
| US-5504101-A | TRYPTAMINE ANALOGS | ALLELIX BIOPHARMACEUTICALS, INC. (CA) | 1996-04-02 | — | — | US | disclosed |
| US-5496957-A | 5-HYDOXYTRYPTAMINE | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1996-03-05 | — | — | US | disclosed |
| WO-1995030655-A1 | TRYPTAMINE DERIVATIVES AS 5-HT-1D RECEPTOR LIGANDS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1995-11-16 | — | — | WO | disclosed |
| EP-0666847-A1 | TRYPTAMINE ANALOGS WITH 5-HT1D SELECTIVITY | Allelix Biopharmaceuticals Inc. (CA) | 1995-08-16 | — | — | EP | disclosed |
| WO-1995006638-A1 | TRYPTAMINE ANALOGS WITH 5-HT1D SELECTIVITY | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1995-03-09 | — | — | WO | disclosed |
| US-4252803-A | HYPOTENSIVE AGENTS, ANALGESICS | GLAXO GROUP LIMITED (GB) | 1981-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250346602-A1 | LACTAM SUBSTITUTED IMIDAZOPYRIDAZINE IL-17A MODULATORS AND USES THEREOF | IL17A, IL15, IL18 | L3MBTL1 4848/4885POLB 2245/4885HTT 4861/4885 |
| US-12421232-B2 | Kinase inhibitor compounds and compositions and methods of use | CSNK1A1, DYRK1A, CSNK1G3 | L3MBTL1 3307/4885POLB 1513/4885HTT 1554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.