Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LOX | P28300 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15907 | 0.98 | — | — | |
| SCHEMBL6896419 | 0.82 | MAPT (0.47) | CYP2C9CYP2C19PKMCYP2D6POLB | |
| SCHEMBL8193497 | 0.79 | — | — | |
| SCHEMBL3041710 | 0.79 | HTR6 (0.50) | CYP2C9CYP2C19PKMCYP2D6F2 | |
| SCHEMBL6825084 | 0.78 | CYP2D6 (0.49) | CYP2C9CYP2C19CYP2D6MAPTHPGD | |
| SCHEMBL1336037 | 0.77 | LOX (0.60) | CYP2C9CYP2C19PKMCYP2D6F2 | |
| SCHEMBL15880570 | 0.76 | CYP2C9 (0.36) | CYP2C9CYP2C19PKMCYP2D6F2 | |
| Hydrochloric Acid SCHEMBL8128267 | 0.76 | LMNA (0.45) | CYP2C9CYP2C19PKMCYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL28533417 | 0.75 | LOX (0.58) | CYP2C9CYP2C19PKMCYP2D6F2 | |
| SCHEMBL329263 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658288-B1 | 2-AMINO-5-BENZOYLTHIAZOLE NPY ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2007-12-05 | — | — | EP | disclosed |