SCHEMBL5560693

SCHEMBL5560693

CCCCC=C(C#N)C(=O)OOCCOC

nearest known ligand 0.32

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.32
LMNA P02545 3/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
POLB P06746 1/20 0.32
CYP3A4 P08684 1/20 0.32
GAA P10253 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C19 P33261 1/20 0.32
ALDH1A1 P00352 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MITF O75030 1/20 0.30
HPGD P15428 1/20 0.30
MAPK1 P28482 1/20 0.30
MDM2 Q00987 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7167573 0.93 ALDH1A1 (0.33) CYP2C9LMNAALDH1A1SMN1; SMN2L3MBTL1
SCHEMBL5561382 0.91 CYP2C9 (0.33) CYP2C9LMNAMEN1KMT2AALDH1A1
SCHEMBL6665840 0.90 ALDH1A1 (0.33) ALDH1A1
SCHEMBL29372087 0.90 CYP2C9 (0.34) CYP2C9LMNAMEN1KMT2APOLB
SCHEMBL7165557 0.86 ALDH1A1 (0.33) CYP2C9LMNAMEN1KMT2AALDH1A1
SCHEMBL20261959 0.85 CYP2C9 (0.38) CYP2C9LMNAMEN1KMT2APOLB
SCHEMBL5561659 0.85 CYP2C9 (0.35) CYP2C9LMNAMEN1KMT2APOLB
SCHEMBL16247073 0.83 ALDH1A1 (0.35) CYP2C9LMNAMEN1KMT2APOLB
SCHEMBL540753 0.83 EP300 (0.37) CYP2C9LMNAMEN1KMT2APOLB
SCHEMBL7167564 0.81 DNM1 (0.40) CYP2C9LMNAMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1360257-B1 CYANOACRYLATE COMPOSITIONS CURABLE TO FLEXIBLE POLYMERIC MATERIALS LOCTITE R & D LTD (IE) 2007-07-25 EP claimed
EP-1360257-A1 CYANOACRYLATE COMPOSITIONS CURABLE TO FLEXIBLE POLYMERIC MATERIALS Loctite (R & D) Limited (IE) 2003-11-12 EP claimed
WO-2002053666-A1 CYANOACRYLATE COMPOSITIONS CURABLE TO FLEXIBLE POLYMERIC MATERIALS LOCTITE (R & D) LIMITED (IE) 2002-07-11 WO claimed
EP-1360257-B1 CYANOACRYLATE COMPOSITIONS CURABLE TO FLEXIBLE POLYMERIC MATERIALS LOCTITE R & D LTD (IE) 2007-07-25 EP disclosed
US-6977278-B1 Cyanoacrylate compositions curable to flexible polymeric materials LOCTITE (R&D) LTD. (IE) 2005-12-20 US disclosed
EP-1360257-A1 CYANOACRYLATE COMPOSITIONS CURABLE TO FLEXIBLE POLYMERIC MATERIALS Loctite (R & D) Limited (IE) 2003-11-12 EP disclosed
WO-2002053666-A1 CYANOACRYLATE COMPOSITIONS CURABLE TO FLEXIBLE POLYMERIC MATERIALS LOCTITE (R & D) LIMITED (IE) 2002-07-11 WO disclosed