Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5560697 | 0.81 | AXL (0.57) | AXLMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7979367 | 0.76 | PDE3B (0.51) | MAPTMEN1KMT2AGAAMAPK1 | |
| SCHEMBL2892328 | 0.76 | AXL (0.46) | AXLMAPTMEN1KMT2AGAA | |
| SCHEMBL13335345 | 0.75 | AXL (0.67) | AXLMAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL5561143 | 0.75 | AXL (0.67) | AXLMAPTMEN1KMT2AGAA | |
| SCHEMBL20279531 | 0.75 | AXL (0.67) | AXLMAPTMEN1KMT2AGAA | |
| SCHEMBL5561070 | 0.75 | AXL (0.67) | AXLMAPTMEN1KMT2ANOTUM | |
| SCHEMBL11846026 | 0.75 | AXL (0.92) | AXLMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2375581 | 0.74 | AXL (1.00) | AXLMAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL10802190 | 0.74 | MAPT (0.42) | MAPTMEN1KMT2AGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262201-B1 | For the manufacture of a medicament for use in the production of an antiangiogenic and/or vascular permeability reducing effect in warm-blooded animals | ASTRAZENECA AB (SE) | 2007-08-28 | — | — | US | disclosed |