Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 18/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 18/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450867 | 0.83 | PDE3B (0.53) | PDE3BPDE3AMAPT | |
| SCHEMBL7976918 | 0.78 | PDE3B (0.70) | PDE3BPDE3A | |
| SCHEMBL4693648 | 0.78 | PDE3B (0.70) | PDE3BPDE3A | |
| SCHEMBL261632 | 0.78 | PDE3A (0.65) | PDE3BPDE3A | |
| SCHEMBL251865 | 0.77 | PDE3B (0.67) | PDE3BPDE3A | |
| SCHEMBL4321214 | 0.76 | MAPT (0.57) | GAAMEN1MAPTMAPK1KMT2A | |
| SCHEMBL5560748 | 0.76 | AXL (0.59) | GAAMEN1MAPTMAPK1KMT2A | |
| SCHEMBL11248109 | 0.75 | PDE3B (0.50) | PDE3BPDE3A | |
| SCHEMBL9669173 | 0.74 | PDE3B (0.52) | PDE3BPDE3A | |
| SCHEMBL9668897 | 0.73 | MAOB (0.56) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001000601-A1 | NOVEL 4-(2-OXODIHYDROOXADIAZINYLPHENYL)AMIDES AND THE USE THEREOF FOR TREATING ANEMIA | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-04 | — | — | WO | disclosed |