Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 4/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | KIF5B | P33176 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5564793 | 0.88 | KDR (0.40) | HSD17B2L3MBTL1KDRRETKIF5B | |
| Iodide SCHEMBL5565778 | 0.87 | KDR (0.41) | HSD17B2L3MBTL1KDRRETKIF5B | |
| Hydrochloric Acid SCHEMBL5565999 | 0.87 | KDR (0.41) | HSD17B2L3MBTL1KDRRETKIF5B | |
| SCHEMBL6130234 | 0.82 | TUBB4A (0.48) | HSD17B2L3MBTL1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL5560529 | 0.73 | PIK3CG (0.31) | L3MBTL1KDR | |
| Hydrochloric Acid SCHEMBL5565982 | 0.70 | ALDH1A1 (0.40) | HSD17B2L3MBTL1KDRRETKIF5B | |
| SCHEMBL20544415 | 0.70 | BCHE (0.37) | L3MBTL1APOBEC3AAPOBEC3GPABPC1ALDH1A1 | |
| SCHEMBL11689059 | 0.69 | USP2 (0.42) | ALDH1A1BCHEUSP2 | |
| SCHEMBL7555415 | 0.69 | HPGD (0.54) | L3MBTL1KDRALDH1A1EGFRMEN1 | |
| Fluoride Ion SCHEMBL18740626 | 0.68 | HDAC8 (0.48) | L3MBTL1APOBEC3AAPOBEC3GPABPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229479-B2 | Method of coloring porous material | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-06-12 | — | — | US | disclosed |
| US-20060162095-A1 | Method of colouring porous material | CIBA SPECIALTY CHEMICALS CORP. | 2006-07-27 | — | — | US | disclosed |
| EP-1534226-A1 | METHOD OF COLOURING POROUS MATERIAL | Ciba SC Holding AG (CH) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004019897-A1 | METHOD OF COLOURING POROUS MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060162095-A1 | Method of colouring porous material | ACR, HLA-C, TYR | HSD17B2 1251/4885L3MBTL1 4611/4885KDR 4077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.