Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.31 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.31 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5555837 | 0.90 | PTGER4 (0.39) | PTGDR2 | |
| SCHEMBL5561735 | 0.88 | MAPT (0.37) | CARM1PRMT6PTGDR2KCNJ6KCNJ5 | |
| SCHEMBL5556006 | 0.88 | PTGDR2 (0.41) | CARM1PRMT6PTGDR2MAPT | |
| SCHEMBL5557512 | 0.88 | PTGDR2 (0.33) | CARM1PRMT6PTGDR2MAPT | |
| SCHEMBL5556070 | 0.87 | SIRT1 (0.34) | CARM1PRMT6PTGDR2MAPT | |
| SCHEMBL5561125 | 0.86 | MEN1 (0.37) | KCNJ6KCNJ5KCNJ3MAPT | |
| SCHEMBL5555856 | 0.85 | MAPT (0.37) | PTGDR2MAPTPTGS2RECQL | |
| SCHEMBL14453992 | 0.83 | MAPT (0.36) | PTGDR2MAPT | |
| SCHEMBL5560864 | 0.83 | CYP1A2 (0.31) | CARM1PRMT6MAPT | |
| SCHEMBL5556124 | 0.83 | EPAS1 (0.38) | CARM1PRMT6PTGDR2MAPTP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597235-B1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2007-08-15 | — | — | EP | disclosed |
| US-7241794-B2 | Nonnucleoside reverse transcriptase inhibitors | ROCHEPALO ALTO LLC (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241794-B2 | Nonnucleoside reverse transcriptase inhibitors | ROCHEPALO ALTO LLC (US) | 2007-07-10 | — | — | US | disclosed |