Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.53 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5565068 | 0.81 | NPC1 (0.51) | CNR1HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL6455155 | 0.81 | HDAC3 (0.65) | HDAC3HDAC4HDAC1HDAC6NAMPT | |
| SCHEMBL5560316 | 0.81 | MRGPRX4 (0.49) | HDAC3HDAC4HDAC1HDAC6TRPV1 | |
| SCHEMBL14100173 | 0.79 | RAB9A (0.57) | CNR1NAMPTLMNARAB9ACLK1 | |
| SCHEMBL3577619 | 0.79 | TRPV1 (0.69) | CNR1HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL5565747 | 0.78 | SMN1; SMN2 (0.50) | HDAC3HDAC4HDAC1HDAC6NAMPT | |
| SCHEMBL27422506 | 0.77 | CNR1 (0.67) | CNR1TRPV1NAMPTMAPK14CHRM2 | |
| SCHEMBL7643257 | 0.77 | CNR1 (0.63) | CNR1TRPV1NAMPTMAPK14CHRM2 | |
| SCHEMBL3391028 | 0.76 | TRPV1 (0.65) | CNR1TRPV1NAMPTMAPK14RAB9A | |
| SCHEMBL6989302 | 0.75 | CNR1 (0.58) | CNR1HDAC3HDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758880-A1 | HYDROXAMATES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005121119-A1 | HYDROXAMATES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-12-22 | — | — | WO | disclosed |