Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19149257 | 0.89 | LMNA (0.51) | HSD11B1ALDH1A1LMNAGRIN2DGRIN3B | |
| SCHEMBL20659918 | 0.88 | ALDH1A1 (0.46) | HSD11B1ALDH1A1LMNAGRIN2DGRIN3B | |
| SCHEMBL20672519 | 0.88 | ALDH1A1 (0.46) | HSD11B1ALDH1A1LMNAGRIN2DGRIN3B | |
| SCHEMBL29462032 | 0.88 | ALDH1A1 (0.46) | HSD11B1ALDH1A1LMNAGRIN2DGRIN3B | |
| SCHEMBL20660265 | 0.88 | ALDH1A1 (0.46) | HSD11B1ALDH1A1LMNAGRIN2DGRIN3B | |
| SCHEMBL24139484 | 0.88 | HSD11B1 (0.46) | HSD11B1ALDH1A1LMNAGRIN2DGRIN3B | |
| SCHEMBL20659904 | 0.88 | ALDH1A1 (0.46) | HSD11B1ALDH1A1LMNAGRIN2DGRIN3B | |
| SCHEMBL20672518 | 0.88 | ALDH1A1 (0.46) | HSD11B1ALDH1A1LMNAGRIN2DGRIN3B | |
| SCHEMBL20660352 | 0.88 | ALDH1A1 (0.46) | HSD11B1ALDH1A1LMNAGRIN2DGRIN3B | |
| SCHEMBL19149359 | 0.86 | HSD11B1 (0.71) | HSD11B1ALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3405183-A1 | ADAMATANE DERIVATIVES FOR THE TREATMENT OF FILOVIRUS INFECTION | Arisan Therapeutics Inc. (US) | 2018-11-28 | — | — | EP | disclosed |
| WO-2017127306-A1 | ADAMATANE DERIVATIVES FOR THE TREATMENT OF FILOVIRUS INFECTION | ARISAN THERAPEUTICS (US) | 2017-07-27 | — | — | WO | disclosed |
| US-20070078256-A1 | Prepolymers, prepolymer compositions, high-molecular-weight polymers with pore structure, and dielectric films | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
| EP-1683822-A1 | PREPOLYMER, PREPOLYMER COMPOSITION, HIGH MOLECULAR WEIGHT POLYMER HAVING STRUCTURE CONTAINING HOLE AND ELECTRICALLY INSULATING FILM | Daicel Chemical Industries, Ltd. (JP) | 2006-07-26 | — | — | EP | disclosed |