SCHEMBL5564342

SCHEMBL5564342

NC(CCCC(N)C(=O)OC(=O)[C@@H](N)CCC(=O)O)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 2/20 0.67
GRM8 O00222 2/20 0.67
GRM6 O15303 2/20 0.67
GRM7 Q14831 2/20 0.67
GRM4 Q14833 2/20 0.67
CYP1A2 P05177 2/20 0.67
GRIN2D O15399 1/20 0.67
GRIN3B O60391 1/20 0.67
GRIK1 P39086 1/20 0.67
GRM5 P41594 1/20 0.67
GRIA1 P42261 1/20 0.67
GRIA2 P42262 1/20 0.67
GRIA3 P42263 1/20 0.67
SLC1A3 P43003 1/20 0.67
SLC1A2 P43004 1/20 0.67
SLC1A1 P43005 1/20 0.67
GRIA4 P48058 1/20 0.67
GRIN1 Q05586 1/20 0.67
GRIN2A Q12879 1/20 0.67
GRIK2 Q13002 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamic Acid SCHEMBL6034836 0.90 GSR (0.65) GSRGRM8GRM6GRM7GRM4
SCHEMBL4959221 0.88 GRM8 (0.62) GSRGRM8GRM6GRM7GRM4
Glutamic Acid SCHEMBL5565411 0.88 GSR (0.86) GSRGRM8GRM6GRM7GRM4
SCHEMBL496858 0.88 GRM8 (0.62) GSRGRM8GRM6GRM7GRM4
Hydrochloric Acid SCHEMBL10636419 0.86 GRM8 (0.60) GSRGRM8GRM6GRM7GRM4
SCHEMBL31206935 0.85 GRM8 (0.67) GSRGRM8GRM6GRM7GRM4
SCHEMBL20508769 0.85 GRM8 (0.67) GSRGRM8GRM6GRM7GRM4
SCHEMBL890611 0.84 GSR (0.55) GSRGRM8GRM6GRM7GRM4
SCHEMBL28310305 0.84 GSR (0.55) GSRGRM8GRM6GRM7GRM4
Glutamic Acid SCHEMBL27517274 0.84 GRM8 (0.64) GSRGRM8GRM6GRM7GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160160296-A1 BIOMARKERS FOR COLORECTAL CANCER BGI SHENZHEN (CN) 2016-06-09 US disclosed
US-7183101-B2 NCC2705—the genome of a bifidobacterium NESTEC S.A. (CH) 2007-02-27 US disclosed
EP-1360299-A2 THE GENOME OF A BIFIDOBACTERIUM SOCIETE DES PRODUITS NESTLE S.A. (CH) 2003-11-12 EP disclosed
WO-2002074798-A2 THE GENOME OF A BIFIDOBACTERIUM SOCIETE DES PRODUITS NESTLE S.A. (CH) 2002-09-26 WO disclosed