Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.65 |
| ▸ | GRM8 | O00222 | 1/20 | 0.58 |
| ▸ | GRM6 | O15303 | 1/20 | 0.58 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.58 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.58 |
| ▸ | GRM5 | P41594 | 1/20 | 0.58 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.58 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.58 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.58 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.58 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.58 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.58 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.58 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.58 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.58 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.58 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.58 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28310305 | 0.95 | GSR (0.55) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL890611 | 0.95 | GSR (0.55) | GSRGRM8GRM6GRIN2DGRIN3B | |
| Glutamic Acid SCHEMBL27871403 | 0.92 | GSR (0.62) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL5564342 | 0.90 | GSR (0.67) | GSRGRM8GRM6GRIN2DGRIN3B | |
| Lysine SCHEMBL28806096 | 0.90 | GSR (0.74) | GSRCYP1A2BLMNFKB1ARG2 | |
| Lysine SCHEMBL1079952 | 0.90 | GSR (0.80) | GSRGRM8GRM6GRIN2DGRIN3B | |
| Lysine SCHEMBL8000334 | 0.90 | GSR (0.80) | GSRGRM8GRM6GRIN2DGRIN3B | |
| Lysine SCHEMBL890044 | 0.90 | GSR (0.80) | GSRGRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL21796040 | 0.90 | GSR (0.80) | GSRGRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL2415481 | 0.90 | GSR (0.80) | GSRGRM8GRM6GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1475098-B1 | HIGH-CONCENTRATION PREPARATION OF SOLUBLE THROMBOMODULIN | ASAHI KASEI PHARMA CORP (JP) | 2015-08-05 | — | — | EP | disclosed |
| US-20060083733-A1 | High-concentration preparation of soluble thrombomodulin | ASAHI KASEI PHARMA CORPORATION (JP) | 2006-04-20 | — | — | US | disclosed |
| EP-1475098-A1 | HIGH-CONCENTRATION PREPARATION OF SOLUBLE THROMBOMODULIN | Asahi Kasei Pharma Corporation (JP) | 2004-11-10 | — | — | EP | disclosed |