Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.86 |
| ▸ | MEN1 | O00255 | 3/20 | 0.86 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.86 |
| ▸ | PKM | P14618 | 3/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.85 |
| ▸ | HTT | P42858 | 3/20 | 0.85 |
| ▸ | POLB | P06746 | 1/20 | 0.85 |
| ▸ | USP2 | O75604 | 1/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15945283 | 1.00 | KMT2A (0.86) | KMT2AMEN1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL18484219 | 1.00 | KMT2A (0.86) | KMT2AMEN1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL3812763 | 1.00 | KMT2A (0.86) | KMT2AMEN1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL7645597 | 1.00 | KMT2A (0.86) | KMT2AMEN1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL436674 | 0.98 | PKM (0.89) | KMT2AMEN1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL31476293 | 0.96 | ALDH1A1 (0.92) | KMT2AMEN1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL10409988 | 0.94 | PKM (0.96) | KMT2AMEN1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL4102676 | 0.94 | PKM (0.96) | KMT2AMEN1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL8193968 | 0.94 | PKM (0.96) | KMT2AMEN1SMN1; SMN2PKMALDH1A1 | |
| Aziridine SCHEMBL22778235 | 0.93 | KMT2A (0.76) | KMT2AMEN1SMN1; SMN2PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186710-B2 | Phthalazinones | ALTANA PHARMA AG (DE) | 2007-03-06 | — | — | US | disclosed |
| US-20040127707-A1 | PDE4/7 inhibitors useful in treatment of airway disorders, autoimmune system disorders, skin disorders, arthritis, nerve system disorders | ALTANA PHARMA AG (DE) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127707-A1 | PDE4/7 inhibitors useful in treatment of airway disorders, autoimmune system disorders, skin disorders, arthritis, nerve system disorders | PDE4A, PDE4B, PDE7B | KMT2A 3900/4885MEN1 2426/4885SMN1; SMN2 1487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.