Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 6/20 | 0.33 |
| ▸ | RAB9A | P51151 | 6/20 | 0.33 |
| ▸ | ALPL | P05186 | 3/20 | 0.33 |
| ▸ | ALPG | P10696 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ESRRA | P11474 | 1/20 | 0.33 |
| ▸ | ALPP | P05187 | 1/20 | 0.33 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1943217 | 0.79 | PTGER4 (0.44) | ALDH1A1NPC1RAB9AALPLALPG | |
| SCHEMBL3555267 | 0.77 | ALDH1A1 (0.34) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL25647219 | 0.75 | ALPL (0.36) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL5564213 | 0.73 | BRD4 (0.50) | KMT2AALDH1A1LRRK2NPC1RAB9A | |
| SCHEMBL5563949 | 0.72 | ALDH1A1 (0.33) | KMT2AMEN1ALDH1A1NAMPTNPC1 | |
| SCHEMBL16426895 | 0.71 | ALDH1A1 (0.36) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL21783726 | 0.69 | POLB (0.39) | KMT2AMEN1ALDH1A1LRRK2NPC1 | |
| SCHEMBL5656259 | 0.68 | KDM4A (0.45) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1942259 | 0.68 | PTGER4 (0.35) | ALDH1A1NPC1RAB9AALPLALPG | |
| SCHEMBL2119014 | 0.67 | KDM4E (0.52) | ALDH1A1ALPLALPGMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756067-A1 | 7-SUBSTITUTED BENZIMIDAZOLES AND THEIR USE AS INHIBITORS OF GASTRIC ACID SECRETION | Altana Pharma AG (DE) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005111000-A1 | 7-SUBSTITUTED BENZIMIDAZOLES AND THEIR USE AS INHIBITORS OF GASTRIC ACID SECRETION | ALTANA PHARMA AG (DE) | 2005-11-24 | — | — | WO | disclosed |