Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5564853 | 1.00 | ACE (0.45) | ACEMME | |
| SCHEMBL5563609 | 0.91 | DRD2 (0.41) | ACEMME | |
| SCHEMBL5563656 | 0.88 | MC4R (0.41) | ACEMME | |
| SCHEMBL7668349 | 0.88 | MC4R (0.42) | ACE | |
| SCHEMBL5563362 | 0.88 | MC4R (0.42) | ACE | |
| SCHEMBL5377148 | 0.84 | ACE (0.60) | ACEMME | |
| SCHEMBL5563795 | 0.84 | TSHR (0.44) | — | |
| SCHEMBL5563800 | 0.84 | TSHR (0.44) | — | |
| 2,2,2-Trifluoroethanaminium SCHEMBL8213280 | 0.82 | SCN9A (0.40) | — | |
| Trifluoroacetamide SCHEMBL8213276 | 0.82 | SCN9A (0.40) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042288-B1 | TRIPEPTIDYL PEPTIDASE INHIBITORS | INST NAT SANTE RECH MED (FR) | 2007-11-07 | — | — | EP | disclosed |
| US-6335360-B1 | INDOLINE-2-CARBOXYLIC AMIDE DERIVATIVES; OBESITY, EATING AND PSYCHOLOGICAL DISORDERS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2002-01-01 | — | — | US | disclosed |
| EP-1042288-A1 | TRIPEPTIDYL PEPTIDASE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033801-A1 | TRIPEPTIDYL PEPTIDASE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1999-07-08 | — | — | WO | disclosed |