SCHEMBL5565522

SCHEMBL5565522

SCCN(CCS)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
IDO1 P14902 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
EGFR P00533 1/20 0.38
ERBB2 P04626 1/20 0.38
TAAR1 Q96RJ0 2/20 0.37
CYP2C19 P33261 2/20 0.37
CYP2D6 P10635 1/20 0.36
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 1/20 0.35
GLA P06280 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
ALDH1A1 P00352 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ALOX15 P16050 1/20 0.35
HTR2A P28223 1/20 0.34
HRH1 P35367 1/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19771743 0.89 TSHR (0.45) TSHREGFRERBB2TAAR1SMN1; SMN2
SCHEMBL2464780 0.89 TSHR (0.55) TSHRTDP1TAAR1MAPTSMN1; SMN2
SCHEMBL10650495 0.87 TSHR (0.59) TSHRIDO1TAAR1CYP2C19CYP2D6
SCHEMBL9186359 0.83 KCNH2 (0.46) MEN1KMT2A
SCHEMBL8954883 0.81 IDO1 (0.38) TSHRIDO1TDP1TAAR1CYP2C19
SCHEMBL10649088 0.81 KCNH2 (0.45) IDO1TDP1TAAR1
SCHEMBL16896982 0.80 EGFR (0.41) TDP1EGFRERBB2TAAR1CYP2C19
SCHEMBL11501576 0.79 TAAR1 (0.50) TSHREGFRERBB2TAAR1MAPT
SCHEMBL2467097 0.77 TDP1 (0.46) TSHRTDP1TAAR1ALDH1A1HTR2A
SCHEMBL9190295 0.76 KCNH2 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9194981-B2 Mercaptofunctional high mubeta EO chromophores and high TG, low optical loss, covalently bonded, high mubeta EO chromophore containing polymers and methods of synthesizing EO materials CORNING INCORPORATED (US) 2015-11-24 US disclosed
US-9194981-B2 Mercaptofunctional high mubeta EO chromophores and high TG, low optical loss, covalently bonded, high mubeta EO chromophore containing polymers and methods of synthesizing EO materials CORNING INCORPORATED (US) 2015-11-24 US disclosed
EP-2450355-B1 Mercaptofunctional high uB EO chromophores and high tg, low optical loss, covalently bonded, high uB EO chromophore containing polymers and methods of synthesizing EO materials CORNING INC (US) 2014-09-10 EP disclosed
US-20140246631-A1 MERCAPTOFUNCTIONAL HIGH MUBETA EO CHROMOPHORES AND HIGH TG, LOW OPTICAL LOSS, COVALENTLY BONDED, HIGH MUBETA EO CHROMOPHORE CONTAINING POLYMERS AND METHODS OF SYNTHESIZING EO MATERIALS CORNING INCORPORATED (US) 2014-09-04 US disclosed
US-20140246631-A1 MERCAPTOFUNCTIONAL HIGH MUBETA EO CHROMOPHORES AND HIGH TG, LOW OPTICAL LOSS, COVALENTLY BONDED, HIGH MUBETA EO CHROMOPHORE CONTAINING POLYMERS AND METHODS OF SYNTHESIZING EO MATERIALS CORNING INCORPORATED (US) 2014-09-04 US disclosed
US-8754187-B2 Mercaptofunctional high μβ EO chromophores and high Tg, low optical loss, covalently bonded, high μβ EO chromophore containing polymers and methods of synthesizing EO materials CORNING INCORPORATED (US) 2014-06-17 US disclosed
US-8754187-B2 Mercaptofunctional high μβ EO chromophores and high Tg, low optical loss, covalently bonded, high μβ EO chromophore containing polymers and methods of synthesizing EO materials CORNING INCORPORATED (US) 2014-06-17 US disclosed
US-20130270494-A1 MERCAPTOFUNCTIONAL HIGH MUBETA EO CHROMOPHORES AND HIGH TG, LOW OPTICAL LOSS, COVALENTLY BONDED, HIGH MUBETA EO CHROMOPHORE CONTAINING POLYMERS AND METHODS OF SYNTHESIZING EO MATERIALS CORNING INC (US) 2013-10-17 US disclosed
US-20130270494-A1 MERCAPTOFUNCTIONAL HIGH MUBETA EO CHROMOPHORES AND HIGH TG, LOW OPTICAL LOSS, COVALENTLY BONDED, HIGH MUBETA EO CHROMOPHORE CONTAINING POLYMERS AND METHODS OF SYNTHESIZING EO MATERIALS CORNING INC (US) 2013-10-17 US disclosed
US-8481672-B2 Mercaptofunctional high μβ EO chromophores and high Tg, low optical loss, covalently bonded, high μβ EO chromophore containing polymers and methods of synthesizing EO materials CORNING INCORPORATED (US) 2013-07-09 US disclosed
US-20100193753-A1 MERCAPTOFUNCTIONAL HIGH MUBETA EO CHROMOPHORES AND HIGH TG, LOW OPTICAL LOSS, COVALENTLY BONDED, HIGH MUBETA EO CHROMOPHORE CONTAINING POLYMERS AND METHODS OF SYNTHESIZING EO MATERIALS HE MINGQIAN 2010-08-05 US disclosed
US-20100193753-A1 MERCAPTOFUNCTIONAL HIGH MUBETA EO CHROMOPHORES AND HIGH TG, LOW OPTICAL LOSS, COVALENTLY BONDED, HIGH MUBETA EO CHROMOPHORE CONTAINING POLYMERS AND METHODS OF SYNTHESIZING EO MATERIALS HE MINGQIAN 2010-08-05 US disclosed
US-7723462-B2 electrooptic (EO) devices; chromophores bond to polyimidosulfide polymers producing high glass transition temperature, low optical loss CORNING INCORPORATED (US) 2010-05-25 US disclosed
US-7723462-B2 electrooptic (EO) devices; chromophores bond to polyimidosulfide polymers producing high glass transition temperature, low optical loss CORNING INCORPORATED (US) 2010-05-25 US disclosed
WO-2007133414-A2 MERCAPTOFUNCTIONAL HIGH 'MU-BETA' UB EO CHROMOPHORES AND HIGH TG, LOW OPTICAL LOSS, COVALENTLY BONDED, POLYMERS CONTAINING SAID CHROMOPHORES AND METHODS OF SYNTHESIZING EO MATERIALS CORNING INCORPORATED (US) 2007-11-22 WO disclosed
US-20070257237-A1 electrooptic (EO) devices; chromophores bond to polyimidosulfide polymers producing high glass transition temperature, low optical loss CORNING INCORPORATED 2007-11-08 US disclosed
US-20070257237-A1 electrooptic (EO) devices; chromophores bond to polyimidosulfide polymers producing high glass transition temperature, low optical loss CORNING INCORPORATED 2007-11-08 US disclosed
US-6641804-B1 Resin and a diluent, the resin (T) providing a resin film having at least one resin selected from the group consisting of vinyl resins, polyester resins, polyamide resins, silicone resins, cationic urethane resins, ampholytic urethane resins SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2003-11-04 US disclosed
EP-1068859-A1 HAIR TREATMENT AND METHOD OF TREATING HAIR SANYO CHEMICAL INDUSTRIES, Ltd. (JP) 2001-01-17 EP disclosed
EP-0304134-A2 Magnetic resin composition DSM N.V. (NL) 1989-02-22 EP disclosed