SCHEMBL8954883

SCHEMBL8954883

SCCN(S)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.38
TDP1 Q9NUW8 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
ALDH1A1 P00352 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MEN1 O00255 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 1/20 0.33
HTR2A P28223 1/20 0.33
HRH1 P35367 1/20 0.33
ALOX15 P16050 1/20 0.33
TP53 P04637 1/20 0.32
KCNH2 Q12809 1/20 0.32
HTT P42858 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5565522 0.81 TSHR (0.43) IDO1TDP1TAAR1ALDH1A1NPSR1
SCHEMBL10649088 0.79 KCNH2 (0.45) IDO1TDP1TAAR1KCNH2
SCHEMBL16035772 0.77 ALDH1A1 (0.37) ALDH1A1NPSR1MEN1CYP3A4CYP2C9
SCHEMBL28348633 0.77 KDM4E (0.44) TDP1ALDH1A1NPSR1MEN1CYP3A4
SCHEMBL12833638 0.77 TP53 (0.44) ALDH1A1TSHRTP53KCNH2
SCHEMBL2467097 0.75 TDP1 (0.46) TDP1TAAR1ALDH1A1MEN1KMT2A
SCHEMBL18460748 0.73 ALDH1A1 (0.38) TDP1ALDH1A1NPSR1MEN1CYP3A4
SCHEMBL7495273 0.73 TDP1 (0.46) TDP1NPSR1MEN1KMT2ASMN1; SMN2
Hydrochloric Acid SCHEMBL28327279 0.73 TDP1 (0.43) TDP1TAAR1ALDH1A1MEN1KMT2A
SCHEMBL19771743 0.72 TSHR (0.45) TAAR1ALDH1A1NPSR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0362804-B1 Electrophotographic photoreceptor FUJI PHOTO FILM CO LTD (JP) 1996-01-03 EP disclosed
US-5009975-A Binder resin blend, moisture resistant FUJI PHOTO FILM CO., LTD. (JP) 1991-04-23 US disclosed
EP-0362804-A2 Electrophotographic photoreceptor FUJI PHOTO FILM CO., LTD. (JP) 1990-04-11 EP disclosed