Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.32 |
| ▸ | HTR3B | O95264 | 2/20 | 0.32 |
| ▸ | HTR3A | P46098 | 2/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylpiperazine SCHEMBL557578 | 0.83 | PHGDH (0.32) | PHGDHADRB1HTR3EHTR3BHTR3A | |
| Methylpiperazine SCHEMBL12678252 | 0.81 | — | — | |
| Aziridine SCHEMBL736208 | 0.81 | HIF1A (0.36) | — | |
| Methylpiperazine SCHEMBL54849 | 0.81 | — | — | |
| Methylpiperazine SCHEMBL12678256 | 0.81 | — | — | |
| Methylpiperazine SCHEMBL1363 | 0.81 | — | — | |
| Methylpiperazine SCHEMBL12678259 | 0.81 | — | — | |
| SCHEMBL154155 | 0.81 | PHGDH (0.41) | PHGDHADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL1044666 | 0.78 | PHGDH (0.45) | PHGDHADRB1 | |
| SCHEMBL8200625 | 0.78 | HIF1A (0.43) | PHGDHADRB1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9074032-B2 | Membranes based on polyvinyl alcohol | WACKER CHEMIE AG (DE) | 2015-07-07 | — | — | US | disclosed |
| US-8137590-B2 | Particles comprising zwitterionic structural elements | WACKER CHEMIE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-20120031843-A1 | Membranes based on polyvinyl alcohol | WACKER CHEMIE AG (DE) | 2012-02-09 | — | — | US | disclosed |
| US-20080286628-A1 | Particles Comprising Zwitterionic Structural Elements | WACKER CHEMIE AG (DE) | 2008-11-20 | — | — | US | disclosed |