SCHEMBL5566441

SCHEMBL5566441

O=C(CCc1ccccc1)[C@@]1(n2ccc(=O)[nH]c2=O)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.40
SLC28A2 O43868 1/20 0.40
SLC29A1 Q99808 1/20 0.40
SLC28A3 Q9HAS3 1/20 0.40
DUT P33316 1/20 0.35
P2RY14 Q15391 1/20 0.35
GBA1 P04062 1/20 0.34
SLC5A1 P13866 1/20 0.34
SLC5A2 P31639 1/20 0.34
TK2 O00142 1/20 0.33
P2RY2 P41231 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
NT5E P21589 1/20 0.32
FKBP1A P62942 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29094237 0.93 SLC28A1 (0.42) SLC28A1SLC28A2SLC29A1SLC28A3DUT
SCHEMBL5567272 0.85 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL21411505 0.84 SLC28A1 (0.47) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL2995481 0.83 SLC28A1 (0.41) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL2995593 0.83 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3DUT
SCHEMBL31438972 0.83 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL15531959 0.83 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL31438971 0.83 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL5566818 0.82 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL28649290 0.82 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070160554-A1 Acyl ribonucleosides and acyl deoxyribonucleosides, compositions of, and methods of making same COGNIS IP MANAGEMENT GMBH (DE) 2007-07-12 US claimed
EP-1680435-A1 ACYL RIBONUCLEOSIDES AND ACYL DEOXYRIBONUCLEOSIDES Cognis IP Management GmbH (DE) 2006-07-19 EP claimed
WO-2005049633-A1 ACYL RIBONUCLEOSIDES AND ACYL DEOXYRIBONUCLEOSIDES COGNIS IP MANAGEMENT GMBH (DE) 2005-06-02 WO claimed
US-20070160554-A1 Acyl ribonucleosides and acyl deoxyribonucleosides, compositions of, and methods of making same COGNIS IP MANAGEMENT GMBH (DE) 2007-07-12 US disclosed
EP-1680435-A1 ACYL RIBONUCLEOSIDES AND ACYL DEOXYRIBONUCLEOSIDES Cognis IP Management GmbH (DE) 2006-07-19 EP disclosed
WO-2005049633-A1 ACYL RIBONUCLEOSIDES AND ACYL DEOXYRIBONUCLEOSIDES COGNIS IP MANAGEMENT GMBH (DE) 2005-06-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070160554-A1 Acyl ribonucleosides and acyl deoxyribonucleosides, compositions of, and methods of making same RNASEL, RNASEH1, DUT SLC28A1 1568/4885SLC28A2 1262/4885SLC29A1 1279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.