Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96752 | 0.89 | TSHR (0.64) | TSHRIDO1AGXTSMN1; SMN2NAAA | |
| SCHEMBL8062638 | 0.85 | TSHR (0.58) | TSHRIDO1AGXTSMN1; SMN2NAAA | |
| SCHEMBL10316554 | 0.85 | TSHR (0.58) | TSHRIDO1AGXTSMN1; SMN2NAAA | |
| SCHEMBL223907 | 0.84 | TSHR (0.78) | TSHRIDO1AGXTLMNACA1 | |
| SCHEMBL9575414 | 0.82 | TSHR (0.67) | TSHRIDO1AGXTSMN1; SMN2NAAA | |
| SCHEMBL53267 | 0.82 | TSHR (0.74) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL70291 | 0.82 | TSHR (0.74) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL21156064 | 0.79 | TSHR (0.56) | TSHRIDO1AGXTNAAACA1 | |
| SCHEMBL14673418 | 0.79 | TSHR (0.56) | TSHRIDO1AGXTSMN1; SMN2NAAA | |
| SCHEMBL14673871 | 0.79 | TSHR (0.56) | TSHRIDO1AGXTNAAACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229480-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-06-12 | — | — | US | claimed |