Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | AGXT | P21549 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8062638 | 0.96 | TSHR (0.58) | TSHRNAAAIDO1SMN1; SMN2HTT | |
| SCHEMBL10316554 | 0.96 | TSHR (0.58) | TSHRNAAAIDO1SMN1; SMN2HTT | |
| SCHEMBL5566634 | 0.89 | TSHR (0.56) | TSHRNAAAIDO1SMN1; SMN2HTT | |
| SCHEMBL2067114 | 0.86 | TSHR (0.58) | TSHRNAAAIDO1SMN1; SMN2HTT | |
| SCHEMBL1991359 | 0.85 | TSHR (0.78) | TSHRNAAAIDO1SMN1; SMN2HTT | |
| SCHEMBL96048 | 0.85 | TSHR (0.56) | TSHRNAAASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL9489789 | 0.84 | TSHR (0.61) | TSHRNAAAIDO1SMN1; SMN2HTT | |
| SCHEMBL97794 | 0.83 | L3MBTL1 (0.54) | TSHRNAAASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL96808 | 0.83 | L3MBTL1 (0.54) | TSHRNAAASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL9329653 | 0.83 | TSHR (0.54) | TSHRNAAAIDO1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239868-A | Carbamate substituted styryl sulfone compound and preparation method and application thereof | 华夏生生药业(北京)有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-107252429-B | Novel anti-inflammatory agent | 雷斯韦洛吉克斯公司 | 2023-06-16 | — | — | CN | claimed |
| EP-4001263-A1 | CARBAMATE-SUBSTITUTED STYRYL SULFONE COMPOUND, PREPARATION METHOD, AND APPLICATION THEREOF | Huaxiashengsheng Pharmaceutical Beijing Co., Ltd. (CN) | 2022-05-25 | — | — | EP | claimed |
| CN-114072380-A | Carbamate substituted styryl sulfone compound and preparation method and application thereof | 华夏生生药业(北京)有限公司 | 2022-02-18 | — | — | CN | claimed |
| US-10918640-B2 | Azetidine derivatives | VERNALIS (R&D) LTD. (GB) | 2021-02-16 | — | — | US | claimed |
| US-10383871-B2 | Azetidine derivatives | VERNALIS (R&D) LTD. (GB) | 2019-08-20 | — | — | US | claimed |
| EP-2421533-B1 | NOVEL ANTI-INFLAMMATORY AGENTS | RESVERLOGIX CORP (CA) | 2018-10-17 | — | — | EP | claimed |
| US-20170326143-A1 | NOVEL ANTI-INFLAMMATORY AGENTS | HEPALINK (HONG KONG) LIMITED (HK) | 2017-11-16 | — | — | US | claimed |
| CN-107252429-A | New antiinflammatory | 雷斯韦洛吉克斯公司 | 2017-10-17 | — | — | CN | claimed |
| US-20170196864-A1 | Azetidine Derivatives | VERNALIS DEVELOPMENT LIMITED (GB) | 2017-07-13 | — | — | US | claimed |
| US-4891057-A | Phenylpyrazolecarboxylic acid derivatives, their preparation, and their use as plant-growth regulators and safeners | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-02 | — | — | US | claimed |
| EP-0331529-A2 | Diphenyl ether derivatives, process for producing the same and insecticide and acaricide containing the same as active ingredient | UBE INDUSTRIES, LTD. (JP) | 1989-09-06 | — | — | EP | claimed |
| EP-0269806-A1 | Phenylpyrazole carbonic acid derivatives, their preparation and use as plant growth regulators and antidotes | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-06-08 | — | — | EP | claimed |
| US-4747868-A | Growth-regulating, fungicidal, and herbicidal cyclohexylimidazole and cyclohexenylimidazole derivatives, compositions, and methods of use therefor | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | claimed |
| EP-0243918-A2 | 1-Phenyl-imidazole compounds, process for their preparation and their use as growth regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-11-04 | — | — | EP | claimed |
| EP-0219798-A1 | 1,2,5-Substituted imidazole compounds, method for their preparation and their use as growth regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-29 | — | — | EP | claimed |
| EP-0199206-A2 | Cyclohexyl- and cyclohexenylimidazole compounds, process for their preparation and their use as plant-protective agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-10-29 | — | — | EP | claimed |
| EP-0186977-A2 | Renin-inhibitory dipeptides, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1986-07-09 | — | — | EP | claimed |
| EP-0185961-A2 | 1-Phenyl-imidazole-5-carboxylic acid derivatives, process for their preparation and their use as growth regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-07-02 | — | — | EP | claimed |
| US-4011320-A | PESTICIDES, FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1977-03-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10918640-B2 | Azetidine derivatives | FAAH2, FAAH, APEH | TSHR 1911/4885NAAA 160/4885IDO1 55/4885 |
| US-20170196864-A1 | Azetidine Derivatives | FAAH2, FAAH, APEH | TSHR 1911/4885NAAA 160/4885IDO1 55/4885 |
| US-10383871-B2 | Azetidine derivatives | FAAH2, FAAH, APEH | TSHR 1911/4885NAAA 160/4885IDO1 55/4885 |
| US-20170326143-A1 | NOVEL ANTI-INFLAMMATORY AGENTS | VCAM1, ICAM1, IL6 | TSHR 4123/4885NAAA 3748/4885IDO1 712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.