SCHEMBL5567264

SCHEMBL5567264

Cc1sc2ccsc2c1C

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 2/20 0.38
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
MAPT P10636 3/20 0.31
TSHR P16473 1/20 0.31
GAA P10253 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HTT P42858 1/20 0.31
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13671831 0.85 GPR35 (0.35) GPR35ADORA2AADORA1
SCHEMBL18876136 0.77 GPR35 (0.36) GPR35
SCHEMBL24445357 0.77 GPR35 (0.36) GPR35
SCHEMBL18876222 0.77 GPR35 (0.36) GPR35
SCHEMBL18876156 0.77 GPR35 (0.36) GPR35MAPTGAAKDM4EALDH1A1
SCHEMBL12211754 0.74 GPR35 (0.37) GPR35MAPTTSHRGAAKDM4E
SCHEMBL16476054 0.74 GPR35 (0.34) GPR35MAPTHTT
SCHEMBL18876127 0.74 GPR35 (0.39) GPR35ADORA2AADORA1MAPT
SCHEMBL18876124 0.74 GPR35 (0.34) GPR35ADORA2AADORA1
SCHEMBL24595789 0.74 GPR35 (0.34) GPR35GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016124694-A1 LIGHT ABSORBER Technische Universität Dresden (DE) 2016-08-11 WO claimed
US-20230210006-A1 ORGANIC PHOTOVOLTAIC CELLS AND NON-FULLERENE ACCEPTORS THEREOF THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2023-06-29 US disclosed
US-20230180602-A1 KEY MATERIALS FOR ORGANIC PHOTOVOLTAICS RELIABILITY UNITED STATES DEPARTMENT OF ENERGY 2023-06-08 US disclosed
US-20230167139-A1 PHOTOCHROMIC GERMOLE-FUSED DIARYLETHENES AND PRODUCTION THEREOF THE UNIVERSITY OF HONG KONG (CN) 2023-06-01 US disclosed
US-11193065-B2 Liquid crystal composition, method of producing the same, and retardation film constituted from the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-12-07 US disclosed
US-11183637-B2 Organic photodetector Raynergy Tek Incorporation (TW) 2021-11-23 US disclosed
US-20200165519-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND RETARDATION PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-05-28 US disclosed
US-20200052216-A1 ORGANIC PHOTODETECTOR MERCK PATENT GMBH (DE) 2020-02-13 US disclosed
US-20190276744-A1 LIQUID CRYSTAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-09-12 US disclosed
US-10407619-B2 Liquid crystal composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-09-10 US disclosed
US-20110217642-A1 CHARGE TRANSPORT PARTICLES XEROX CORPORATION (US) 2011-09-08 US disclosed
US-20100227157-A1 COMPOSITE STRUCTURED ORGANIC FILMS XEROX CORPORATION (US) 2010-09-09 US disclosed
US-20100227998-A1 STRUCTURED ORGANIC FILMS XEROX CORPORATION (US) 2010-09-09 US disclosed
US-20100227081-A1 MIXED SOLVENT PROCESS FOR PREPARING STRUCTURED ORGANIC FILMS XEROX CORPORATION (US) 2010-09-09 US disclosed
US-20100227071-A1 PROCESS FOR PREPARING STRUCTURED ORGANIC FILMS (SOFS) VIA A PRE-SOF XEROX CORPORATION (US) 2010-09-09 US disclosed
CN-101693722-A Polymerisable thieno not 3,2-b thiophenes MERCK PATENT GMBH 2010-04-14 CN disclosed
CN-1964980-A Polymerizable thieno [3, 2-b ] thiophenes MERCK PATENT GMBH (DE) 2007-05-16 CN disclosed
CN-1956988-A Mono-, oligo-and polythieno [3, 2-b ] thiophenes MERCK PATENT GMBH (DE) 2007-05-02 CN disclosed
EP-1753768-A1 POLYMERISABLE THIENO¬3,2-b|THIOPHENES Merck Patent GmbH (DE) 2007-02-21 EP disclosed
WO-2005121150-A1 POLYMERISABLE THIENO[3,2-b]THIOPHENES MERCK PATENT GMBH (DE) 2005-12-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167139-A1 PHOTOCHROMIC GERMOLE-FUSED DIARYLETHENES AND PRODUCTION THEREOF AGL, GMNN, GAK GPR35 41/4885ADORA2A 1684/4885ADORA1 3368/4885
US-10407619-B2 Liquid crystal composition RCC1, CCDC47, ACIN1 GPR35 3861/4885ADORA2A 1778/4885ADORA1 1484/4885
US-20100227998-A1 STRUCTURED ORGANIC FILMS VIM, PUF60, EPCAM GPR35 4795/4885ADORA2A 4555/4885ADORA1 4790/4885
US-20230210006-A1 ORGANIC PHOTOVOLTAIC CELLS AND NON-FULLERENE ACCEPTORS THEREOF VDAC1, KCNN4, CACNG4 GPR35 4204/4885ADORA2A 4623/4885ADORA1 4679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.