SCHEMBL5567370

SCHEMBL5567370

O=C(Cl)C12CC3CC(CC(C3)C1(C(=O)Cl)C(=O)Cl)C2

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 6/20 0.40
EPHX1 P07099 2/20 0.40
LMNA P02545 2/20 0.34
GAA P10253 2/20 0.34
JAK2 O60674 1/20 0.34
ALDH1A1 P00352 1/20 0.34
RAB9A P51151 1/20 0.34
HTT P42858 1/20 0.33
THRB P10828 1/20 0.32
CYP2C9 P11712 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6860976 0.78 GAA (0.38) EPHX2EPHX1LMNAGAAALDH1A1
SCHEMBL4582380 0.74 EPHX2 (0.40) EPHX2EPHX1GAAALDH1A1THRB
SCHEMBL9504752 0.72 EPHX1 (0.39) EPHX2EPHX1GAAALDH1A1KMT2A
SCHEMBL5832574 0.72 EPHX2 (0.39) EPHX2EPHX1ALDH1A1HTTTHRB
SCHEMBL6859448 0.72 EPHX2 (0.39) EPHX2EPHX1GAAALDH1A1HTT
SCHEMBL6854139 0.72 KMT2A (0.35) EPHX2LMNAGAAALDH1A1KMT2A
SCHEMBL5563682 0.70 EPHX2 (0.34) EPHX2EPHX1LMNAGAAALDH1A1
SCHEMBL927164 0.70 P2RX7 (0.42) EPHX2EPHX1LMNAGAAJAK2
SCHEMBL5832577 0.69 THRB (0.37) EPHX2EPHX1ALDH1A1HTTTHRB
SCHEMBL31666231 0.67 EPHX1 (0.35) EPHX2EPHX1GAAALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070078256-A1 Prepolymers, prepolymer compositions, high-molecular-weight polymers with pore structure, and dielectric films DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-04-05 US disclosed
EP-1683822-A1 PREPOLYMER, PREPOLYMER COMPOSITION, HIGH MOLECULAR WEIGHT POLYMER HAVING STRUCTURE CONTAINING HOLE AND ELECTRICALLY INSULATING FILM Daicel Chemical Industries, Ltd. (JP) 2006-07-26 EP disclosed
US-6794528-B2 HEAT RESISTANCE, FLAME RETARDERS, STABILIZERS; REACTING DIALCOHOL COMPOUND WITH A PHOSPHYL OXYCHLORIDE COMPOUND DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-21 US disclosed
US-20030109736-A1 Phosphorus compound DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-06-12 US disclosed
EP-1277758-A1 PHOSPHORUS COMPOUND Daicel Chemical Industries, Ltd. (JP) 2003-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030109736-A1 Phosphorus compound NR4A1, POLL, NR0B1 EPHX2 3620/4885EPHX1 3912/4885LMNA 3695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.