Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1804626 | 0.88 | MLYCD (0.49) | MLYCDLMNAPOLBHPGDALDH1A1 | |
| SCHEMBL1813086 | 0.80 | MLYCD (0.51) | MLYCDALDH1A1 | |
| SCHEMBL1811315 | 0.73 | CCR2 (0.51) | — | |
| SCHEMBL4414741 | 0.71 | MAPK14 (0.42) | MLYCD | |
| SCHEMBL1813000 | 0.71 | F10 (0.48) | — | |
| SCHEMBL4420743 | 0.71 | HSD11B1 (0.45) | MLYCDLMNAHPGDALDH1A1 | |
| SCHEMBL4418588 | 0.68 | MLYCD (0.57) | MLYCD | |
| SCHEMBL1808820 | 0.67 | BRD4 (0.52) | LMNAHPGDALDH1A1 | |
| SCHEMBL1803545 | 0.67 | MLYCD (0.58) | MLYCD | |
| SCHEMBL6846321 | 0.67 | MLYCD (1.00) | MLYCDLMNAPOLBHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756096-A1 | INDOLYL DERIVATIVES AS LIVER-X-RECEPTOR MODULATORS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005105791-A1 | INDOLYL DERIVATIVES AS LIVER-X-RECEPTOR MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-11-10 | — | — | WO | disclosed |