Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777712 | 0.85 | GAA (0.54) | GAALMNASMN1; SMN2AGTR1KMT2A | |
| SCHEMBL4768157 | 0.83 | GAA (0.70) | GAALMNASMN1; SMN2AGTR1ALDH1A1 | |
| SCHEMBL4767863 | 0.81 | GAA (0.61) | GAALMNASMN1; SMN2AGTR1KMT2A | |
| SCHEMBL5572197 | 0.81 | GAA (0.56) | GAALMNASMN1; SMN2AGTR1KMT2A | |
| SCHEMBL4793661 | 0.81 | LMNA (0.49) | GAALMNASMN1; SMN2AGTR1KMT2A | |
| SCHEMBL4777340 | 0.80 | GAA (0.52) | GAALMNASMN1; SMN2AGTR1NPSR1 | |
| SCHEMBL5567953 | 0.80 | PPARG (0.42) | KMT2AMEN1ALDH1A1NPSR1RORC | |
| SCHEMBL4773262 | 0.79 | GAA (0.54) | GAALMNASMN1; SMN2AGTR1KMT2A | |
| SCHEMBL4792578 | 0.79 | LMNA (0.53) | GAALMNASMN1; SMN2AGTR1ALDH1A1 | |
| SCHEMBL4773154 | 0.79 | GAA (0.55) | GAALMNASMN1; SMN2AGTR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070135435-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-06-14 | — | — | US | claimed |
| US-20070135435-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135435-A1 | Certain chemical entities, compositions, and methods | KIF5B, KIF2C, PLK1 | GAA 466/4885LMNA 1022/4885SMN1; SMN2 1149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.