SCHEMBL5568047

SCHEMBL5568047

CCCCCCCCCCCCCCCC(=O)[C@@]1(n2ccc(=O)[nH]c2=O)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.40
SLC28A2 O43868 1/20 0.40
SLC29A1 Q99808 1/20 0.40
SLC28A3 Q9HAS3 1/20 0.40
TK2 O00142 4/20 0.38
P2RY14 Q15391 1/20 0.35
PRKCA P17252 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5566818 1.00 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3TK2
SCHEMBL28649290 1.00 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3TK2
SCHEMBL2984128 1.00 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3TK2
SCHEMBL28181052 1.00 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3TK2
SCHEMBL2995481 0.96 SLC28A1 (0.41) SLC28A1SLC28A2SLC29A1SLC28A3TK2
SCHEMBL5566803 0.94 SLC28A1 (0.36) SLC28A1SLC28A2SLC29A1SLC28A3TK2
SCHEMBL5567272 0.92 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL15531959 0.87 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL15346466 0.85 P2RY6 (0.38) TK2
SCHEMBL25402419 0.83 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070160554-A1 Acyl ribonucleosides and acyl deoxyribonucleosides, compositions of, and methods of making same COGNIS IP MANAGEMENT GMBH (DE) 2007-07-12 US claimed
EP-1680435-A1 ACYL RIBONUCLEOSIDES AND ACYL DEOXYRIBONUCLEOSIDES Cognis IP Management GmbH (DE) 2006-07-19 EP claimed
WO-2005049633-A1 ACYL RIBONUCLEOSIDES AND ACYL DEOXYRIBONUCLEOSIDES COGNIS IP MANAGEMENT GMBH (DE) 2005-06-02 WO claimed
EP-0257378-A1 Pyrimidine derivatives, their preparation and medicaments containing these derivatives F. HOFFMANN-LA ROCHE AG (CH) 1988-03-02 EP claimed
US-20070160554-A1 Acyl ribonucleosides and acyl deoxyribonucleosides, compositions of, and methods of making same COGNIS IP MANAGEMENT GMBH (DE) 2007-07-12 US disclosed
EP-1680435-A1 ACYL RIBONUCLEOSIDES AND ACYL DEOXYRIBONUCLEOSIDES Cognis IP Management GmbH (DE) 2006-07-19 EP disclosed
WO-2005049633-A1 ACYL RIBONUCLEOSIDES AND ACYL DEOXYRIBONUCLEOSIDES COGNIS IP MANAGEMENT GMBH (DE) 2005-06-02 WO disclosed
EP-0257378-A1 Pyrimidine derivatives, their preparation and medicaments containing these derivatives F. HOFFMANN-LA ROCHE AG (CH) 1988-03-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070160554-A1 Acyl ribonucleosides and acyl deoxyribonucleosides, compositions of, and methods of making same RNASEL, RNASEH1, DUT SLC28A1 1568/4885SLC28A2 1262/4885SLC29A1 1279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.