Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.55 |
| ▸ | PGR | P06401 | 3/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.49 |
| ▸ | MDH1 | P40925 | 2/20 | 0.49 |
| ▸ | MDH2 | P40926 | 2/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5563784 | 0.94 | HIF1A (0.51) | HIF1APGREPHX2EPAS1MDH1 | |
| SCHEMBL5081782 | 0.90 | HIF1A (0.51) | HIF1APGREPHX2EPAS1MDH1 | |
| SCHEMBL5141270 | 0.85 | HIF1A (0.47) | HIF1APGREPHX2EPAS1MDH1 | |
| SCHEMBL5481142 | 0.85 | HIF1A (0.47) | HIF1APGREPHX2EPAS1MDH1 | |
| SCHEMBL5080982 | 0.85 | CA1 (0.55) | SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL11553208 | 0.84 | PGR (0.45) | HIF1APGREPHX2EPAS1MDH1 | |
| SCHEMBL23210638 | 0.84 | HIF1A (0.64) | HIF1AEPHX2EPAS1MDH1MDH2 | |
| SCHEMBL22453109 | 0.84 | HIF1A (0.64) | HIF1APGREPHX2EPAS1MDH1 | |
| SCHEMBL2745792 | 0.80 | PGR (0.50) | PGRLMNAMEN1KMT2ANPC1 | |
| SCHEMBL5470752 | 0.79 | TSHR (0.50) | SMN1; SMN2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078256-A1 | Prepolymers, prepolymer compositions, high-molecular-weight polymers with pore structure, and dielectric films | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
| EP-1683822-A1 | PREPOLYMER, PREPOLYMER COMPOSITION, HIGH MOLECULAR WEIGHT POLYMER HAVING STRUCTURE CONTAINING HOLE AND ELECTRICALLY INSULATING FILM | Daicel Chemical Industries, Ltd. (JP) | 2006-07-26 | — | — | EP | disclosed |
| US-4142036-A | Polyphenylcarboxylic acid adamantane compounds and polymers prepared therefrom | STANDARD OIL COMPANY (INDIANA) (US) | 1979-02-27 | — | — | US | disclosed |