Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.42 |
| ▸ | MDH1 | P40925 | 2/20 | 0.42 |
| ▸ | MDH2 | P40926 | 2/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5141270 | 1.00 | HIF1A (0.47) | HIF1ATSHREPHX2EPAS1MDH1 | |
| SCHEMBL5081782 | 0.94 | HIF1A (0.51) | HIF1ATSHREPHX2EPAS1MDH1 | |
| SCHEMBL5563784 | 0.92 | HIF1A (0.51) | HIF1AEPHX2EPAS1MDH1MDH2 | |
| SCHEMBL5470752 | 0.89 | TSHR (0.50) | TSHRCA1CA2TDP1CA12 | |
| SCHEMBL5480370 | 0.89 | TSHR (0.50) | TSHRCA1CA2TDP1CA12 | |
| SCHEMBL5478519 | 0.89 | TSHR (0.50) | TSHRCA1CA2TDP1CA12 | |
| SCHEMBL5084601 | 0.87 | TSHR (0.46) | HIF1ATSHREPHX2EPAS1CA1 | |
| SCHEMBL5568166 | 0.85 | HIF1A (0.55) | HIF1AEPHX2EPAS1MDH1MDH2 | |
| SCHEMBL5568183 | 0.83 | GRIN2D (0.44) | TSHRPGRALDH1A1GRIN2B | |
| SCHEMBL5080982 | 0.82 | CA1 (0.55) | TSHRCA1CA2TDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078256-A1 | Prepolymers, prepolymer compositions, high-molecular-weight polymers with pore structure, and dielectric films | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
| US-7186454-B2 | Dielectric films and materials therefor | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-03-06 | — | — | US | disclosed |
| US-20070032556-A1 | Aromatic polyamine derivative | DAICEL CHEMICAL INSUSTRIES, LTD. (JP) | 2007-02-08 | — | — | US | disclosed |
| US-20060264667-A1 | Adamantanetricarboxylic acid derivatives | NAGANO SHINYA | 2006-11-23 | — | — | US | disclosed |
| US-7102027-B2 | Adamantanetricarboxylic acid derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2006-09-05 | — | — | US | disclosed |
| EP-1683822-A1 | PREPOLYMER, PREPOLYMER COMPOSITION, HIGH MOLECULAR WEIGHT POLYMER HAVING STRUCTURE CONTAINING HOLE AND ELECTRICALLY INSULATING FILM | Daicel Chemical Industries, Ltd. (JP) | 2006-07-26 | — | — | EP | disclosed |
| EP-1681284-A1 | AROMATIC POLYAMINE DERIVATIVE | Daicel Chemical Industries, Ltd. (JP) | 2006-07-19 | — | — | EP | disclosed |
| US-20040242923-A1 | Adamantanetricarboxylic acid derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2004-12-02 | — | — | US | disclosed |
| US-20040175858-A1 | Dielectric films and materials therefor | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242923-A1 | Adamantanetricarboxylic acid derivatives | HCAR1, CA1, ALDH7A1 | HIF1A 86/4885TSHR 2353/4885EPHX2 1271/4885 |
| US-20070032556-A1 | Aromatic polyamine derivative | SRM, PRMT1, KDM8 | HIF1A 698/4885TSHR 1167/4885EPHX2 1144/4885 |
| US-20060264667-A1 | Adamantanetricarboxylic acid derivatives | CA1, HCAR1, ALDH7A1 | HIF1A 122/4885TSHR 2048/4885EPHX2 1405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.