⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL341697 | 0.85 | — | — | |
| Nitric Acid SCHEMBL11880438 | 0.84 | CA5A (0.38) | — | |
| SCHEMBL342458 | 0.83 | — | — | |
| SCHEMBL9748437 | 0.79 | — | — | |
| SCHEMBL11401617 | 0.79 | ALDH1A1 (0.32) | — | |
| SCHEMBL8955012 | 0.77 | FDPS (0.34) | — | |
| SCHEMBL9578451 | 0.75 | FDPS (0.38) | — | |
| SCHEMBL9430178 | 0.74 | — | — | |
| SCHEMBL17219792 | 0.74 | GGPS1 (0.41) | — | |
| SCHEMBL9186664 | 0.73 | MEN1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 504 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114349595-B | Method for recycling BDO byproducts of allyl alcohol method | 万华化学集团股份有限公司 | 2023-12-19 | — | — | CN | claimed |
| CN-115286484-A | Production process and preparation method of trimethylolethane | 安徽普利优新材料有限公司 | 2022-11-04 | — | — | CN | claimed |
| CN-113354529-B | Method for synthesizing 2, 2-dimethylolpropionic acid by using byproduct 2-hydroxymethylpropanal of BDO device | 万华化学集团股份有限公司 | 2022-09-20 | — | — | CN | claimed |
| CN-114349595-A | Method for recycling by-product of BDO (methanol to ethane) prepared by allyl alcohol method | 万华化学集团股份有限公司 | 2022-04-15 | — | — | CN | claimed |
| CN-113354529-A | Method for synthesizing 2, 2-dimethylolpropionic acid by using byproduct 2-hydroxymethylpropanal of BDO device | 万华化学集团股份有限公司 | 2021-09-07 | — | — | CN | claimed |
| CN-110437050-A | A kind of synthesis technology of 2,2- dihydroxymethyl propionic aldehyde aqueous solution | JIANGXI KEDING CHEMICAL MAT CO LTD | 2019-11-12 | — | — | CN | claimed |
| CN-110305003-A | A kind of process using microreactor continuous production 2,2- dihydromethyl propionic acid | 昆山复希工程技术有限公司 | 2019-10-08 | — | — | CN | claimed |
| CN-110002982-A | The method for preparing polyalcohol | 伊斯曼化学公司 | 2019-07-12 | — | — | CN | claimed |
| EP-2951141-B1 | PROCESS FOR PRODUCING POLYOLS | EASTMAN CHEM CO (US) | 2019-06-19 | — | — | EP | claimed |
| WO-2018104968-A1 | TANNING AGENT COMPOSITION, ITS USE AND PROCESS FOR PREPARATION THEREOF | GG ORGANICS (P) LTD (IN) | 2018-06-14 | — | — | WO | claimed |
| US-20060173033-A1 | Use of rapamycin and rapamycin derivatives for the treatment of bone loss | KNEISSEL MICHAELA | 2006-08-03 | — | — | US | claimed |
| US-20060154952-A1 | Pharmaceutical compositions comprising a combination of rapamycin or its derivative and pimecrolimus for the treatment of inflammation-and ummunologically-mediated diseases | MOORE HENRIETTA | 2006-07-13 | — | — | US | claimed |
| EP-1646634-A1 | USE OF RAPAMYCIN AND RAPAMYCIN DERIVATIVES FOR THE TREATMENT OF BONE LOSS | Novartis AG (CH) | 2006-04-19 | — | — | EP | claimed |
| EP-1608368-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A COMBINATION OF RAPAMYCIN OR ITS DERIVATIVE AND PIMECROLIMUS FOR THE TREATMENT OF INFLAMMATION- AND UMMUNOLOGICALLY-MEDIATED DISEASES | Novartis AG (CH) | 2005-12-28 | — | — | EP | claimed |
| WO-2005049021-A1 | MATERIALS AND METHODS FOR INHIBITING NEOINTIMAL HYPERPLASIA | OY HELSINKI TRANSPLANTATION R & D LTD (FI) | 2005-06-02 | — | — | WO | claimed |
| WO-2005005434-A1 | USE OF RAPAMYCIN AND RAPAMYCIN DERIVATIVES FOR THE TREATMENT OF BONE LOSS | NOVARTIS AG (CH) | 2005-01-20 | — | — | WO | claimed |
| CN-1178915-C | Alkynyl containing hydroxamic acid derivatives, their preparation and their use as matrix metalloproteinase (MMP) inhibitors/TNF-alpha converting enzyme (TACE) inhibitors | ���Ͽع�����˾ | 2004-12-08 | — | — | CN | claimed |
| WO-2004082681-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A COMBINATION OF RAPAMYCIN OR ITS DERIVATIVE AND PIMECROLIMUS FOR THE TREATMENT OF INFLAMMATION- AND UMMUNOLOGICALLY-MEDIATED DISEASES | NOVARTIS AG (CH) | 2004-09-30 | — | — | WO | claimed |
| EP-0119675-A1 | Hydrocarbyl-substituted mono and bis succinimide having polyamine chain linked hydroxyacyl radicals and mineral oil compositions containing same | TEXACO DEVELOPMENT CORPORATION (US) | 1984-09-26 | — | — | EP | claimed |
| US-4313863-A | HYDROLYSIS WITH USE OF ANTISTICKING AGENTS | NITTO CHEMICAL INDUSTRY CO. LTD. (JP) | 1982-02-02 | — | — | US | claimed |