Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | IDE | P14735 | 1/20 | 0.53 |
| ▸ | MPI | P34949 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | DDO | Q99489 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30373749 | 1.00 | KDM4E (0.53) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL28197191 | 0.84 | ALDH1A1 (0.57) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL30366683 | 0.82 | KDM4E (0.62) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL62193 | 0.82 | KDM4E (0.62) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL61857 | 0.81 | MAP2 (0.62) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL10704376 | 0.81 | ALDH1A1 (0.61) | KDM4EALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL30572914 | 0.80 | KDM4E (0.69) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4207606 | 0.80 | KDM4E (0.69) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29150402 | 0.79 | MAP2 (0.51) | KDM4EALDH1A1POLBMEN1KMT2A | |
| SCHEMBL1122596 | 0.79 | ALDH1A1 (0.68) | KDM4EALDH1A1MAPTIDEMPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250236590-A1 | A METHOD FOR THE PREPARATION OF INDOLE-3-CARBOXYLIC ACID DERIVATIVES | DEB INDUBHUSAN | 2025-07-24 | — | — | US | disclosed |
| CN-118265698-A | Process for preparing indole-3-carboxylic acid derivatives | 科学与工业研究会(按照印度社会团体注册法案(1860年第21号法案)设立的注册机构) | 2024-06-28 | — | — | CN | disclosed |
| WO-2023067628-A1 | A METHOD FOR THE PREPARATION OF INDOLE-3-CARBOXYLIC ACID DERIVATIVES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) | 2023-04-27 | — | — | WO | disclosed |
| CN-105325466-B | A kind of composition for inducing plant disease-resistant and coordinate plant growth, and its preparation method and application | 沈阳化工研究院有限公司 | 2018-02-06 | — | — | CN | disclosed |
| CN-105325466-A | Composition for inducing plants to resist diseases and adjusting plant growth and preparation method and application of composition | SHENYANG RES INST CHEMICAL IND | 2016-02-17 | — | — | CN | disclosed |
| EP-1751156-A1 | 6,7,8,9-SUBSTITUTED 1-PHENYL-1,5-DIHYDRO-PYRIDO(3,2-B)INDOL-2-ONES USEFUL AS ANTI-INFECTIVE PHARMACEUTICAL AGENTS | Tibotec Pharmaceuticals Ltd. (IE) | 2007-02-14 | — | — | EP | disclosed |
| EP-1750708-A1 | COMBINATIONS OF SUBSTITUTED 1-PHENYL-1,5-DIHYDRO-PYRIDO- [3,2-B] INDOL-2-ONES AND OTHER HIV INHIBITORS | Tibotec Pharmaceuticals Ltd. (IE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005111035-A1 | 6,7,8,9-SUBSTITUTED 1-PHENYL-1,5-DIHYDRO-PYRIDO[3,2-B]INDOL-2-ONES USEFUL AS ANTI-INFECTIVE PHARMACEUTICAL AGENTS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-11-24 | — | — | WO | disclosed |
| WO-2005110411-A1 | COMBINATIONS OF SUBSTITUTED 1-PHENYL-1,5-DIHYDRO-PYRIDO- [3,2-B] INDOL-2-ONES AND OTHER HIV INHIBITORS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-11-24 | — | — | WO | disclosed |
| EP-1594870-A1 | SUBSTITUTED INDOLEPYRIDINIUM AS ANTI-INFECTIVE COMPOUNDS | Tibotec Pharmaceuticals Ltd. (IE) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004046143-A1 | SUBSTITUTED INDOLEPYRIDINIUM AS ANTI-INFECTIVE COMPOUNDS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2004-06-03 | — | — | WO | disclosed |
| US-5925647-A | TREATMENT OF INSULIN NON-INSULIN DEPENDENT DIABETES | SHAMAN PHARMACEUTICALS, INC. (US) | 1999-07-20 | — | — | US | disclosed |
| US-5681958-A | TREATMENT OF DIABETES | SHAMAN PHARMACEUTICALS, INC. (US) | 1997-10-28 | — | — | US | disclosed |
| WO-1996010015-A1 | CRYPTOLEPINE ANALOGS WITH HYPOGLYCEMIC ACTIVITY | SHAMAN PHARMACEUTICALS, INC. (US) | 1996-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250236590-A1 | A METHOD FOR THE PREPARATION OF INDOLE-3-CARBOXYLIC ACID DERIVATIVES | IDO1, INMT, IDO2 | KDM4E 2274/4885ALDH1A1 608/4885MAPT 1841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.