Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23486367 | 0.92 | KDM4E (0.51) | KDM4E | |
| SCHEMBL23453742 | 0.90 | KDM4E (0.49) | KDM4ESMN1; SMN2POLB | |
| SCHEMBL9026168 | 0.87 | KDM4E (0.58) | KDM4ESMN1; SMN2POLB | |
| SCHEMBL5417372 | 0.86 | KDM4E (0.53) | KDM4ESMN1; SMN2POLB | |
| SCHEMBL23453712 | 0.86 | PDE3B (0.54) | KDM4EPOLB | |
| SCHEMBL23453747 | 0.86 | AR (0.50) | KDM4EPOLB | |
| SCHEMBL4234705 | 0.81 | AR (0.54) | KDM4EPOLB | |
| SCHEMBL23453723 | 0.80 | AR (0.44) | — | |
| SCHEMBL5025427 | 0.79 | ALDH1A1 (0.52) | KDM4ESMN1; SMN2POLB | |
| SCHEMBL16260565 | 0.78 | KDM4E (0.57) | KDM4ESMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863809-A2 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | Coley Pharmaceutical Group, Inc. (US) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006107753-A2 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-10-12 | — | — | WO | disclosed |