Phosphine

Phosphine

SCHEMBL5568847

CCC(O)P(C(O)CC)C(O)CC.P

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL386280 0.96 TSHR (0.44) TSHR
SCHEMBL8010115 0.93 TSHR (0.41) TSHR
SCHEMBL8000848 0.93 TSHR (0.41) TSHR
SCHEMBL8824889 0.82 TSHR (0.33) TSHR
Phosphoric Acid SCHEMBL8824868 0.82 LAP3 (0.40) TSHR
Phosphoric Acid SCHEMBL8824878 0.82 LAP3 (0.40) TSHR
Hypophosphorous Acid SCHEMBL8824894 0.82 TSHR (0.33) TSHR
SCHEMBL14840308 0.80 TSHR (0.44) TSHR
SCHEMBL11045121 0.78 TSHR (0.42) TSHR
Acetic Acid SCHEMBL8010204 0.78 CA1 (0.40) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7285181-B2 Bleaching and brightness stabilization of lignocellulosic materials with water-soluble phosphines or phosphonium compounds FPINNOVATIONS (CA) 2007-10-23 US claimed
EP-1590525-B1 BLEACHING AND BRIGHTNESS STABILIZATION OF LIGNOCELLULOSIC MATERIALS WITH WATER-SOLUBLE PHOSPINES OR PHOSPHONIUM COMPOUNDS PULP PAPER RES INST (CA) 2006-10-25 EP claimed
EP-1590525-A1 BLEACHING AND BRIGHTNESS STABILIZATION OF LIGNOCELLULOSIC MATERIALS WITH WATER-SOLUBLE PHOSPINES OR PHOSPHONIUM COMPOUNDS Pulp and Paper Research Institute of Canada (CA) 2005-11-02 EP claimed
US-20040173328-A1 Bleaching and brightness stabilization of lignocellulosic materials with water-soluble phosphines or phosphonium compounds FPINNOVATIONS (CA) 2004-09-09 US claimed
WO-2004070110-A1 BLEACHING AND BRIGHTNESS STABILIZATION OF LIGNOCELLULOSIC MATERIALS WITH WATER-SOLUBLE PHOSPHINES OR PHOSPHONIUM COMPOUNDS PULP AND PAPER RESEARCH INSTITUTE OF CANADA (CA) 2004-08-19 WO claimed